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Page d'accueilToutes les moléculesTGF-beta 3
TGF-beta 3
TGF-beta 3 Informations sur la molécule
| Nom anglais | Transforming growth factor beta 3 | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 3 | Alias de la cible | Transforming Growth Factor beta3，TGFB3，LAP，Prepro-Transforming Growth Factor Beta-3，TGF-Beta3，Transforming Growth Factor， Beta 3，ARVD1，LDS5，Arrhythmogenic Right Ventricular Dysplasia 1，RNHF，Transforming growth factor beta-3 proprotein，ARVD |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Transforming growth factor beta 3 |
| Alias de la cible | Transforming Growth Factor beta3，TGFB3，LAP，Prepro-Transforming Growth Factor Beta-3，TGF-Beta3，Transforming Growth Factor， Beta 3，ARVD1，LDS5，Arrhythmogenic Right Ventricular Dysplasia 1，RNHF，Transforming growth factor beta-3 proprotein，ARVD |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 3 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
TGF-beta 3 Liste de produits
- Attribut
Protein (3)
- Bibliothèque de produits
En ligne (3)
- Espèces
Human (3)
- Étiquette
Tag Free (1)His Tag & Avi Tag (1)His Tag (1)
- Marqueur
Unconjugated (2)Biotin-labeled (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human TGF-beta 3 / TGFB3 Protein, premium grade |  |  |  |  Ajouter au panier | |
| Human | HEK293 | Human Latent TGF-beta 3 / Latent TGFB3 Protein, His Tag |  | |  | Ajouter au panier | |
| Human | HEK293 | Biotinylated Human Latent TGF-beta 3 / Latent TGFB3 Protein, His,Avitag™ |  | | | Ajouter au panier |
Quantité totale3
- 1
TGF-beta 3Contexte de la molécule
Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
TGF-beta 3Alias de la molécule
TGFB3,ARVD,TGF-beta3
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Dalutrafusp alfa | GS-1423; AGEN-1423 | Phase 2 Clinical | Agenus Inc | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Liver Neoplasms; Pancreatic Neoplasms; Solid tumours | Details |
| RG-6315 | RG-6315 | Phase 1 Clinical | Genentech Inc | Scleroderma, Systemic | Details |
| BMS-986416 | BMS-986416; AVID-200 DP; AVID-200 | Phase 1 Clinical | Formation Biologics Corp | Polycythemia Vera; Primary Myelofibrosis; Scleroderma, Diffuse; Solid tumours; Thrombocythemia, Essential | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments cliniques
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