TIM-4

TIM-4 Informations sur la molécule

Nom anglais	T-cell immunoglobulin and mucin domain-containing protein 4	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	T-cell immunoglobulin mucin receptor 4 (TIM-4)，T-cell membrane protein 4，TIM4
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	T-cell immunoglobulin and mucin domain-containing protein 4
Alias de la cible	T-cell immunoglobulin mucin receptor 4 (TIM-4)，T-cell membrane protein 4，TIM4
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 1 Clinical

TIM-4 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
His Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
TI4-H52H3	Human	HEK293	Human TIM-4 / TIMD4 Protein, His Tag				Ajouter au panier

Quantité totale1

TIM-4Contexte de la molécule

The T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance. An essential step during clearance of apoptotic cells is the recognition of phosphatidylserine (PS) exposed on apoptotic cells by its receptors on phagocytes. The phosphatidylserine (PS) receptor Tim-4 mediates phagocytosis of apoptotic cells by binding to PS exposed on the surface of these cells, and thus functions as a PS receptor for apoptotic cells. Tim-4 directly binding to PS and functioning as a tethering receptor for phagocytosis of apoptotic cells has been extensively studied over the past decade. However, the molecular mechanisms by which Tim-4 collaborates with other engulfment receptors during efferocytosis remain elusive.

TIM-4Alias de la molécule

TIM4,TIMD4,SMUCKLER

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
LPX-TI641	LPX-TI-641	Phase 1 Clinical	LAPIX Therapeutics Inc	Arthritis, Psoriatic; Arthritis, Rheumatoid; Autoimmune Diseases; Demyelinating Diseases; Dermatitis, Atopic; Multiple Sclerosis; Neuromyelitis Optica; Psoriasis	Details