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TNFR1
TNFR1 Informations sur la molécule
| Nom anglais | Tumor necrosis factor receptor superfamily member 1A | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 | Alias de la cible | Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60 |
| Phase de R&D la plus avancée | Phase 3 Clinical | ||
| Nom anglais | Tumor necrosis factor receptor superfamily member 1A |
| Alias de la cible | Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 2 |
| Phase de R&D la plus avancée | Phase 3 Clinical |
TNFR1 Liste de produits
- Attribut
Protein (10)
- Bibliothèque de produits
En ligne (10)
- Espèces
Human (5)Human & Mouse (2)Porcine (1)Cynomolgus (1)Mouse (1)
- Étiquette
His Tag (5)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)
- Marqueur
Unconjugated (6)Biotin-labeled (4)
Ajouter au panier
Quantité totale10
- 1
TNFR1Contexte de la molécule
Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).
TNFR1Alias de la molécule
TNFR1,CD120a,TNFRSF1A,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR55,TNFR60,p55,p60
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Ofranergene obadenovec | GT-111; VB-111 | Phase 3 Clinical | Vascular Pharmaceuticals Inc | Colorectal Neoplasms; Glioblastoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Thyroid Carcinoma, Anaplastic | Details |
| Atrosab | Phase 1 Clinical | Celonic | Inflammation | Details |
Avis sur les produits
E***a2024-11-13
0Mettre un likeI was able to get this protein shipped overnight and use it for Octet and SPR experiments. Quality is amazing and the biotinylated protein works great!- 1***22019-10-10 0Mettre un likeThe quality of TNFR1 protein is pretty good. I performed the SDS-PAGE. The result shown as below is similar to the result on ACRO's official website. The purity is good, and the position is also the same.
- Informations sur la molécule
- Liste de produits
- Avis sur les produits
- Informations sur les médicaments cliniques
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