TNFR2

TNFR2 Informations sur la molécule

Nom anglais	Tumor necrosis factor receptor superfamily member 1B	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	8	Alias de la cible	TNFR-II，TNFR80，TNF-RII，p80 TNF-alpha receptor，p75，Tumor necrosis factor receptor 2，Etanercept，TBP-2，Tumor necrosis factor receptor type II，TBPII，CD120b，TNF-R-II，CD120b Antigen，Tumor Necrosis Factor Beta Receptor，Soluble TNFR1B Variant 1，Tumor Necrosis Factor Binding Protein 2，TNFBR，TNF Receptor Superfamily Member 1B，TNFR2，P75 TNF Receptor，P75TNFR，TNFR1B，Tumor Necrosis Factor Receptor Superfamily， Member 1B，TNF-R75，TNF-R2
Phase de R&D la plus avancée	Approved

Nom anglais	Tumor necrosis factor receptor superfamily member 1B
Alias de la cible	TNFR-II，TNFR80，TNF-RII，p80 TNF-alpha receptor，p75，Tumor necrosis factor receptor 2，Etanercept，TBP-2，Tumor necrosis factor receptor type II，TBPII，CD120b，TNF-R-II，CD120b Antigen，Tumor Necrosis Factor Beta Receptor，Soluble TNFR1B Variant 1，Tumor Necrosis Factor Binding Protein 2，TNFBR，TNF Receptor Superfamily Member 1B，TNFR2，P75 TNF Receptor，P75TNFR，TNFR1B，Tumor Necrosis Factor Receptor Superfamily， Member 1B，TNF-R75，TNF-R2
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	8
Phase de R&D la plus avancée	Approved

TNFR2 Liste de produits

Attribut
Protein (10)
Bibliothèque de produits
En ligne (10)
Espèces
Human (4)Cynomolgus / Rhesus macaque (1)Mouse (3)Mouse & Human (1)Human & Mouse (1)
Étiquette
His Tag (5)His Tag & Avi Tag (2)Fc Tag (2)Fc Tag & Avi Tag (1)
Marqueur
Unconjugated (7)Biotin-labeled (3)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT TN2-H5227	Human	HEK293	Human TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT TN2-H5253	Human	HEK293	Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified)	Ajouter au panier
HOT TN2-H82E3	Human	HEK293	Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, His,Avitag™ (MALS verified)	Ajouter au panier
HOT TN2-C52H7	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque TNFR2 / CD120b / TNFRSF1B Protein, His Tag	Ajouter au panier
TN2-H82F3	Human	HEK293	Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, Fc,Avitag™ (MALS verified)	Ajouter au panier
TN2-M5254	Mouse	HEK293	Mouse TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified)	Ajouter au panier
TN2-M52H8	Mouse	HEK293	Mouse TNFR2 / CD120b / TNFRSF1B Protein, His Tag	Ajouter au panier
TN2-M82E3	Mouse	HEK293	Biotinylated Mouse TNFR2 / CD120b / TNFRSF1B Protein, His,Avitag™ (MALS verified)	Ajouter au panier
TN2-H52H3	Human & Mouse	HEK293	Human & Mouse TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
TN2-M52H3	Mouse & Human	HEK293	Mouse & Human TNFR2 / CD120b / TNFRSF1B Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier

Quantité totale10

TNFR2Contexte de la molécule

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

TNFR2Alias de la molécule

TNFRSF1B,CD120b,TBPII,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80,p75,p75TNFR

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
LBL-019	LBL-019	Phase 2 Clinical	Nanjing Leadsbiolabs Co Ltd	Neoplasms	Details
BI-1910	BI-1910	Phase 2 Clinical	Bioinvent International Ab	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Solid tumours	Details
BITR-2101	BITR-2101; BIR-2101; BITT2101; BITT-2101	Phase 1 Clinical	Boston Immune Technologies & Therapeutics	Infections; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms	Details
TRB-061	TRB-061	Phase 1 Clinical	Trex Bio Inc	Colitis; Dermatitis; Dermatitis, Atopic	Details
NBL-020		Phase 1 Clinical	Shanghai Xinshi Biological Medicine Co Ltd	Neoplasms; Solid tumours	Details
BC-011	BC-011	Phase 1 Clinical	Dragonboat Biopharmaceutical	Solid tumours	Details
SIM1811-03	SIM1811-03; SIM0235; SIM-235	Phase 1 Clinical	Jiangsu Simcere Pharmaceutical Co Ltd	Lymphoma, T-Cell, Cutaneous; Neoplasms; Solid tumours	Details
Emunkitug	HFB-2003; HFB-200301	Phase 1 Clinical	HiFiBiO Therapeutics	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Germinoma; Melanoma; Mesothelioma; Neoplasm Metastasis; Neoplasms; Sarcoma; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms	Details

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Recombinant human type II tumor necrosis factor receptor-antibody fusion protein(Hisun Biological)		Approved	Hisun Biopharmaceutical Co Ltd		Mainland China	Spondylitis, Ankylosing; Psoriasis; Arthritis, Rheumatoid	Hisun Biopharmaceutical Co Ltd	2015-04-09	Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing	Details