TRBC1

TRBC1 Informations sur la molécule

Nom anglais	TRBC1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	4	Alias de la cible	T cell receptor beta constant 1，TRBC1，V_segment Translation Product，BV05S1J2.2，TCRBC1，TCRB
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	TRBC1
Alias de la cible	T cell receptor beta constant 1，TRBC1，V_segment Translation Product，BV05S1J2.2，TCRBC1，TCRB
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	4
Phase de R&D la plus avancée	Phase 2 Clinical

TRBC1 Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag (1)His Tag & Avi Tag (1)
Marqueur
Unconjugated (1)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
TR1-H52H4	Human	HEK293	Human TRBC1 Protein, His Tag (HPLC verified)				Ajouter au panier
TR1-H82E6	Human	HEK293	Biotinylated Human TRBC1 Protein, His,Avitag™				Ajouter au panier

Quantité totale2

TRBC1Contexte de la molécule

The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRBC1 is the constant region of T-cell receptor (TCR) beta chain. TRBC1 is presented on the surface of T cell and recognized peptide-major histocompatibility (MH) (pMH) that are displayed by antigen presenting cells (APC). TRBC1 is participate in an adaptive immune response and has been well-studied in T cell therapy.

TRBC1Alias de la molécule

T cell receptor beta constant 1,TRBC1

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Invikafusp Alfa	STAR0602; STAR-0602	Phase 2 Clinical	Marengo Therapeutics Inc	Abdominal Neoplasms; Breast Neoplasms; Carcinoma; Epstein-Barr Virus Infections; Lung Neoplasms; Neoplasms; Papillomavirus Infections; Solid tumours; Triple Negative Breast Neoplasms; Urogenital Neoplasms; Vulvar Diseases; Vulvar Neoplasms	Details
TRBC1/2-Targeted CAR-T Cell Therapy (Second Affiliated Hospital School Of Zhejiang University School Of Medicine)		Phase 1 Clinical	Second Affiliated Hospital School Of Zhejiang University School Of Medicine	Lymphoma, T-Cell, Peripheral	Details
Anti-TRBC1 CAR-T cell therapy (Shanghai General Hospital)		Phase 1 Clinical	Shanghai General Hospital	Hematologic Neoplasms	Details
FT-819	FT-8198; FT-819; FT 8198	Phase 1 Clinical	Memorial Sloan Kettering Cancer Center	Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Myositis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Scleroderma, Systemic	Details

Avis sur les produits

1***82022-08-03
0Mettre un like
Human TRBC1 Protein, His Tag (HPLC verified)
The TRBC1 protein is really helpful! Recently, our experiment has not been smooth UNTIL we used the TRBC1 protein and then things finally started to come together! It turns out we were not using the right protein which stopped us from continuing our project. Thank you so much!