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TRGC1

TRGC1 Overview

English Name	T cell receptor gamma variable 9	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	T-Cell Receptor， Gamma， Variable Region V9，TCRGV9，TRGC1
Highest Development Stage	Preclinical

English Name	T cell receptor gamma variable 9
Target Synonym	T-Cell Receptor， Gamma， Variable Region V9，TCRGV9，TRGC1
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

TRGC1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
TR1-H52H3	Human	HEK293	Human TRGC1 Protein, His Tag

Total: 1

TRGC1 Background

The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRGC1 is the constant region of T-cell receptor (TCR) gamma chain. It recognizes the non-peptide antigens frequently expressed at the epithelial boundaries, which means the antigens activating γδ T cells are mostly MHC independent. A wide range of γδ T cell functions have been described in humans and mice, including skin and mucosal epithelial wound repair, induction of tolerance, cytotoxicity and the production of various cytokines that regulate immune responses.