TSHR

TSHR Informations sur la molécule

Nom anglais	Thyroid stimulating hormone receptor	Nombre de médicaments commercialisés	3
Nombre de médicaments cliniques	6	Alias de la cible	TSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
Phase de R&D la plus avancée	Approved

Nom anglais	Thyroid stimulating hormone receptor
Alias de la cible	TSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
Nombre de médicaments commercialisés	3
Nombre de médicaments cliniques	6
Phase de R&D la plus avancée	Approved

TSHR Liste de produits

Attribut
Cell (3)Protein (1)
Bibliothèque de produits
En ligne (4)
Espèces
Human (4)
Étiquette
- (4)
Marqueur
- (3)Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
CHEK-ATF187	Human	HEK293	Human TSHR (Luc) HEK293 Reporter Cell	Ajouter au panier
CHEK-ATP086	Human	HEK293	HEK293/Human TSHR Stable Cell Line	Ajouter au panier
SCCHO-ATP085	Human	CHO	CHO/Human TSHR Stable Cell Line	Ajouter au panier
TSR-H52P3	Human	HEK293	Human TSHR Full Length Protein (VLP)	Ajouter au panier

Quantité totale4

TSHRContexte de la molécule

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

TSHRAlias de la molécule

TSHR,TSH-R,LGR3,TSH R

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Anti-thyroid stimulating hormone receptor chimeric antigen receptor T cell therapy (Innovative Cellular Therapeutics)	ICTCAT-023	Phase 2 Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	Details
ZG-001(Zhigen)	ZG-001(Zhigen); JH-001	Phase 2 Clinical	Hunan Warner Pharmaceutical Factory Chiral Medicine Co Ltd, Hunan Warrant Pharmaceutical Co Ltd, Shanghai Zhigen Pharmaceutical Technology Co Ltd	Depressive Disorder; Depressive Disorder, Major	Details
ICTCAR-051	ICTCAR-051	Phase 1 Clinical	Innovative Cellular Therapeutics Co Ltd	Solid tumours; Thyroid Neoplasms	Details
KSP-0914		Phase 1 Clinical	Kissei Pharmaceutical Co Ltd	Graves Disease	Details
GensSci098	GenSci098; GenSci-098; GensSci-098; GensSci098; GS-098; YB-101	Phase 1 Clinical	Changchun GeneScience Pharmaceuticals Co Ltd	Goiter; Graves Disease; Graves Ophthalmopathy	Details
ICTCAR-TC	ICTCAR-TC	Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	Details

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Thyrotropin alfa	rh-TSH; MRrhTSH; rhTSH-M	Approved	Genzyme Corp	Thyrogen	United States	Thyroid Neoplasms	Genzyme Corp	1998-11-30	Diagnostic agents; Goiter, Nodular; Thyroid Neoplasms	Details
Recombinant human thyrotropin (Zelgen Biosciences)		Approved	Suzhou Zelgen Biosciences Co Ltd	赛诺璟, 泽速宁	Mainland China	Thyroid Neoplasms	Suzhou Zelgen Biopharmaceuticals Co Ltd	2026-01-05	Thyroid Neoplasms	Details
Recombinant human thyroid stimulating hormone(Smartnuclide)	SNA-001; SNA001; KN040; KN-040	Approved	Smartnuclide Biopharma	智舒嘉	Mainland China	Thyroid Neoplasms	Smartnuclide Biopharma	2024-04-02	Thyroid Neoplasms	Details