USAG-1

USAG-1 Informations sur la molécule

Nom anglais	Sclerostin domain-containing protein 1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0	Alias de la cible	SOSTDC1，CDA019，USAG1，Sclerostin Domain Containing 1，DAND7，Sclerostin Domain-Containing Protein 1，Ectodermal BMP Inhibitor，DKFZp564D206，Ectodin，Wise，Uterine Sensitization-Associated Gene 1 Protein，Uterine Sensitization-Associated Protein-1，Cystine-Knot Containing Secreted Protein，ECTODIN
Phase de R&D la plus avancée	Preclinical

Nom anglais	Sclerostin domain-containing protein 1
Alias de la cible	SOSTDC1，CDA019，USAG1，Sclerostin Domain Containing 1，DAND7，Sclerostin Domain-Containing Protein 1，Ectodermal BMP Inhibitor，DKFZp564D206，Ectodin，Wise，Uterine Sensitization-Associated Gene 1 Protein，Uterine Sensitization-Associated Protein-1，Cystine-Knot Containing Secreted Protein，ECTODIN
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	0
Phase de R&D la plus avancée	Preclinical

USAG-1 Liste de produits

Attribut
Protein (1)
Bibliothèque de produits
En ligne (1)
Espèces
Human (1)
Étiquette
Fc Tag (1)
Marqueur
Unconjugated (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
US1-H5254	Human	HEK293	Human USAG-1 Protein, Fc Tag				Ajouter au panier

Quantité totale1

Demande de produit

USAG-1Contexte de la molécule

USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain–containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway.