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Page d'accueilToutes les moléculesVCAM-1
VCAM-1
VCAM-1 Informations sur la molécule
| Nom anglais | Vascular cell adhesion molecule 1 | Nombre de médicaments commercialisés | 2 |
| Nombre de médicaments cliniques | 1 | Alias de la cible | VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1 |
| Phase de R&D la plus avancée | Approved | ||
| Nom anglais | Vascular cell adhesion molecule 1 |
| Alias de la cible | VCAM1，Vascular cell adhesion protein 1，V-CAM 1，CD106，Vascular Cell Adhesion Molecule 1，CD106 Antigen，INCAM-100，VCAM-1，Vascular Cell Adhesion Molecule-1 |
| Nombre de médicaments commercialisés | 2 |
| Nombre de médicaments cliniques | 1 |
| Phase de R&D la plus avancée | Approved |
VCAM-1 Liste de produits
- Attribut
Protein (8)Cell Grade Beads (2)
- Bibliothèque de produits
En ligne (10)
- Espèces
Human (6)- (1)Cynomolgus (2)Mouse (1)
- Étiquette
His Tag (3)Fc Tag (2)Fc Tag & Avi Tag (2)- (2)His Tag & Avi Tag (1)
- Marqueur
Unconjugated (5)Biotin-labeled (3)- (2)
Ajouter au panier
Quantité totale10
- 1
VCAM-1Contexte de la molécule
Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.
VCAM-1Alias de la molécule
VCAM1,CD106,INCAM-100,V-CAM 1,VCAM-1
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| 99mTc-cAbVCAM1-5 | 99mTccAbVCAM1‐5; 99mTc-cAbVCAM1-5 | Phase 1 Clinical | Medico-Economic Evaluation Unit , University Hospital, Grenoble | Atherosclerosis; Cardiovascular Diseases | Details |
Informations sur les médicaments commercialisés
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Plus ancien nom de marque | Pays d'approbation le plus ancien | Indication la plus ancienne | Société d'approbation la plus ancienne | Date d'approbation la plus ancienne | Indication | Essai clinique |
|---|---|---|---|---|---|---|---|---|---|---|
| Tocopherol acetate | DSE-9912 | Approved | National Institute Of Diabetes And Digestive And Kidney Diseases | Ephynal, Aquasol E | Japan | Vitamin E Deficiency; Diabetic Retinopathy; Atherosclerosis; Intermittent Claudication; Venous Thromboembolism; Thrombosis | Eisai Co Ltd | 1951-09-01 | Atherosclerosis; Diabetic Retinopathy; Intermittent Claudication; Metabolic Dysfunction-Associated Steatotic Liver Disease; Thrombosis; Venous Thromboembolism; Vitamin E Deficiency | Details |
| Ascorbic Acid/Biotin/Cholecalciferol/Cyanocobalamin/Dexpanthenol/Folic acid/Niacinamide/Pyridoxine/Riboflavin/Thiamine/Tocopherol Acetate/Vitamin A/Vitamin K | Approved | Sandoz Canada Inc | Infuvite Pediatric | United States | Avitaminosis | Sandoz Canada Inc | 2001-02-21 | Avitaminosis | Details |
- Informations sur la molécule
- Liste de produits
- Informations sur les médicaments commercialisés
- Informations sur les médicaments cliniques
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