VSIG4

VSIG4 Informations sur la molécule

Nom anglais	V-set and immunoglobulin domain-containing protein 4	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1	Alias de la cible	Protein Z39Ig，CRIg，Z39IG
Phase de R&D la plus avancée	Phase 1 Clinical

Nom anglais	V-set and immunoglobulin domain-containing protein 4
Alias de la cible	Protein Z39Ig，CRIg，Z39IG
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	1
Phase de R&D la plus avancée	Phase 1 Clinical

VSIG4 Liste de produits

Attribut
Protein (2)
Bibliothèque de produits
En ligne (2)
Espèces
Human (2)
Étiquette
His Tag (1)His Tag & Avi Tag (1)
Marqueur
Unconjugated (1)Biotin-labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Structure protéique	Pureté	Caractéristiques	Pré-commande/Commande
VS4-H5226	Human	HEK293	Human VSIG4 Protein, His Tag				Ajouter au panier
VS4-H82E3	Human	HEK293	Biotinylated Human VSIG4 Protein, His,Avitag™ (MALS verified)				Ajouter au panier

Quantité totale2

VSIG4Contexte de la molécule

V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.