Monoclonal Anti-NMTi Antibody, Rabbit IgG (M1E05)

Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
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NMI-MY2365-100ug
$315.00
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NMI-MY2365-1mg (500ug X 2)
$1,890.00
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NMI-MY2365
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Source

Monoclonal Anti-NMTi Antibody, Rabbit IgG (M1E05) is a recombinant rabbit monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

M1E05

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit

Immunogen

NMTi-BSA

Specificity

Specifically recognizes NMTi.

Application
Application
Recommended Use
ELISA
0.2-2 μg/mL

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Introduction de fond

NMTi, a new ADC payload toxin developed by Myricx Bio, inhibits NMT to disrupt mitochondrial function and induce endoplasmic reticulum stress, thereby killing cancer cells. Its simple structure facilitates synthesis. In preclinical studies, it exhibits efficacy and safety in solid tumors; NMTi-ADCs feature dual targeting and strong bystander activity, and outperform T-Dxd in some models.