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ACE2
ACE2 Informations sur la molécule
| Nom anglais | Angiotensin-converting enzyme 2 | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 7 | Alias de la cible | Angiotensin-converting enzyme homolog，Metalloprotease MPROT15，ACEH，Angiotensin I Converting Enzyme 2，Angiotensin-converting enzyme-related carboxypeptidase，Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2，Peptidyl-Dipeptidase A，ACE-related carboxypeptidase |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Angiotensin-converting enzyme 2 |
| Alias de la cible | Angiotensin-converting enzyme homolog，Metalloprotease MPROT15，ACEH，Angiotensin I Converting Enzyme 2，Angiotensin-converting enzyme-related carboxypeptidase，Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2，Peptidyl-Dipeptidase A，ACE-related carboxypeptidase |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 7 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
ACE2 Liste de produits
- Attribut
Protein (14)Beads (1)
- Bibliothèque de produits
En ligne (15)
- Espèces
Human (10)Rat (1)Mouse (1)Paguma larvata (1)- (1)Mink (1)
- Étiquette
Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)His Tag (7)Fc Tag (2)- (1)Mouse IgG Fc Tag (1)
- Marqueur
Biotin-labeled (4)Unconjugated (9)- (1)PE Labeled (1)
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Quantité totale15
- 1
- 2
ACE2Contexte de la molécule
Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
ACE2Alias de la molécule
ACE-2,ACEH,ACE2
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| Fexlamose | MUC-031; AER-01 | Phase 2 Clinical | Trinity College Dublin, University College Dublin, University Of California San Francisco | Cystic Fibrosis; Lung Diseases; Pulmonary Disease, Chronic Obstructive | Details |
| NKG2D-ACE2 CAR-NK cell therapy (Sidemu Biotechnology Technology) | Phase 2 Clinical | Chongqing Sidemu Biotechnology Technology Co Ltd | Coronavirus Disease 2019 (COVID-19); Hematologic Neoplasms | Details | |
| HH-120 | HH-120 | Phase 2 Clinical | Huahui Health Ltd | Coronavirus Disease 2019 (COVID-19) | Details |
| SBK-001 | SBK-001 | Phase 2 Clinical | Chengdu Shibeikang Biomedical Technology Co Ltd | Acute Lung Injury; Respiratory Tract Diseases | Details |
| 68Ga-labeled ACE2 Targeting Probe(Peking Union Medical College Hospital) | 68Ga-A3 | Phase 1 Clinical | Peking Union Medical College Hospital | Lung Neoplasms | Details |
| AOD01 | AOD01; AOD-01 | Phase 1 Clinical | A*Star | Coronavirus Disease 2019 (COVID-19) | Details |
| 68Ga-DX600 | Clinical | Beijing Cancer Hospital | Solid tumours | Details |
Avis sur les produits
1***82022-08-06
0Mettre un likeAs always, I trust ACRO’s antibody reagents! According to the technical feedback we’ve gotten, the experimental data is stable and produces good quality charts & graphs which is really helpful for us improve the experimental efficiency and advance the project.- K***k2021-10-08 1Mettre un likeACRO biosystem’s protein has been very useful in research and development for our diagnostic assays! They ship very fast and this product has been reliable so far. ACRO biosystem’s sales representative was very professional and helpful to our team! Their website and catalog is very user friendly and easy for any one to use. We always look forward to working with ACRO biosystems and their llamas!
- X***n2021-09-01 12Mettre un likeWe have been using this antigen since early 2020. We internal QC showed very high quality, in terms of purity, solubility, sequence correctness, stability, etc. This reagent jump started our program. We have been using it in antibody screening funnel as well as blocking assays. It behaves very well in ELISA and SPR. I am also impressed by ACRO Bio's speedy logistic and technical support communications.
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- Informations sur la molécule
- Liste de produits
- Avis sur les produits
- Informations sur les médicaments cliniques
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