Cadherin-3 Informations sur la molécule
Molecule Name
Cadherin 3
Alias de la molécule
CDH3,CDHP,Cadherin-3,P-cadherin
Drug Development Progress
Nombre de médicaments cliniques7
Nombre de médicaments commercialisés0
Phase de R&D la plus avancéePhase 2 Clinical
Alias de la cible
Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD
Contexte de la molécule
Cadherin-3 （also known as P-cadherin）is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.
Cadherin-3 Liste de produits
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Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| STEMVAC | EP-101 | Phase 2 Clinical | Epithany | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; HR-positive breast cancer; Lung Neoplasms; Triple Negative Breast Neoplasms | Details |
| BC-3195 | BC3195; BC-3195 | Phase 2 Clinical | Wuxi BioCity | Neoplasm Metastasis; Neoplasms; Solid tumours | Details |
| FF-21101-Y-90 | FF-21101-Y-90; PPMX-T002 | Phase 1 Clinical | Fujifilm Holdings Corp | Solid tumours | Details |
| FF-21101 | FF-21101 | Phase 1 Clinical | Perseus Proteomics Inc | Bile Duct Neoplasms; Colorectal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours | Details |
| TRAILR2/CDH3 bispecific antibody (Boehringer Ingelheim) | Phase 1 Clinical | Boehringer Ingelheim International Gmbh | Neoplasms | Details | |
| AMG 305 | AMG 305; AMG-305 | Phase 1 Clinical | Amgen Inc | Solid tumours | Details |
| FF-21101In | FF-21101In | Phase 1 Clinical | PeptiDream Inc | Solid tumours | Details |