IL-12 R beta 1

IL-12 R beta 1 Informations sur la molécule

Nom anglais	Interleukin-12 receptor	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	9	Alias de la cible	Receptors， Interleukin-12
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	Interleukin-12 receptor
Alias de la cible	Receptors， Interleukin-12
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	9
Phase de R&D la plus avancée	Phase 2 Clinical

IL-12 R beta 1 Liste de produits

Attribut
Protein (7)
Bibliothèque de produits
En ligne (7)
Espèces
Human (4)Cynomolgus (2)Mouse (1)
Étiquette
His Tag (1)Fc Tag & Avi Tag (1)Fc Tag (2)His Tag & Avi Tag (3)
Marqueur
Unconjugated (3)Biotin-labeled (4)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT ILB-H5255	Human	HEK293	Human IL-12 R beta 1 / CD212 Protein, Fc Tag (MALS verified)	Ajouter au panier
HOT ILB-H52E1	Human	HEK293	Biotinylated Human IL-12 R beta 1 / CD212 Protein, His,Avitag™ (MALS verified)	Ajouter au panier
HOT ILB-H52H9	Human	HEK293	Human IL-12 R beta 1 / CD212 Protein, His Tag (MALS verified)	Ajouter au panier
HOT ILB-H82F7	Human	HEK293	Biotinylated Human IL-12 R beta 1 / CD212 Protein, Fc,Avitag™	Ajouter au panier
ILB-M52E1	Mouse	HEK293	Biotinylated Mouse IL-12 R beta 1 / CD212 Protein, His,Avitag™	Ajouter au panier
ILB-C5253	Cynomolgus	HEK293	Cynomolgus IL-12 R beta 1 Protein, Fc Tag	Ajouter au panier
ILB-C52E2	Cynomolgus	HEK293	Biotinylated Cynomolgus IL-12 R beta 1 / CD212 Protein, His,Avitag™	Ajouter au panier

Quantité totale7

IL-12 R beta 1Contexte de la molécule

The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

IL-12 R beta 1Alias de la molécule

IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
KLT-1101	KLT-1101	Phase 2 Clinical	Kang Litai Pharmaceutical Co Ltd	Leukopenia; Melanoma; Sarcoma, Kaposi; Solid tumours; Thrombocytopenia	Details
Edodekin alfa	RO 247472; YM 01C	Phase 2 Clinical	F. Hoffmann-La Roche Ltd, Valeant, Wistar Institute	Abdominal Neoplasms; Asthma; Bacterial Infections; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Graft vs Host Disease; Hepatitis B; Hepatitis C; HIV Infections; Leishmaniasis; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Malaria; Melanoma; Neoplasms; Sarcoma, Kaposi; Solid tumours; Squamous Cell Carcinoma of Head and Neck	Details
RTX-224	RTX-224	Phase 2 Clinical	Rubius Therapeutics Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms	Details
KB-707	KB707; KB-707	Phase 2 Clinical	Krystal Biotech Inc	Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Melanoma; Neoplasms; Skin Melanoma; Solid tumours	Details
ASP-9801	ASP-9801	Phase 1 Clinical	Astellas Pharma Inc	Neoplasm Metastasis; Neoplasms; Solid tumours	Details
Tolododekin Alfa	ANK101; ANK-101	Phase 1 Clinical	Ankyra Therapeutics Inc	Carcinoma, Basosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Rejection of renal transplantation; Skin Neoplasms; Soft Tissue Injuries; Solid tumours	Details
CLN-617	CLN-617	Phase 1 Clinical	Cullinan Therapeutics Inc	Solid tumours	Details
SON-1010	SON-1010	Phase 1 Clinical	Sonnet Biotherapeutics Inc	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Sarcoma; Solid tumours	Details
phIL12 GET		Phase 1 Clinical	Institute Of Oncology Ljubljana	Carcinoma, Basal Cell	Details

Avis sur les produits

K***n2024-10-05
0Mettre un like
Biotinylated Mouse IL-12 R beta 1 / CD212 Protein, His,Avitag™
I’ve been using the IL12 receptor protein from Acro Biosystem in my antibody discovery research, and I’m highly satisfied with its quality. The protein exhibits excellent stability and bioactivity, which has been crucial in my experiments targeting immune responses. It’s been a reliable reagent, showing consistent results across various assays. I highly recommend this product for anyone involved in immunological research, particularly in therapeutic antibody development.