IL-18
IL-18 Liste de produits
- Attribut
Protein (5)Kits (1)
- Bibliothèque de produits
En ligne (6)
- Espèces
Human (4)Mouse (1)Rhesus macaque (1)
- Étiquette
Tag Free (4)His Tag (1)- (1)
- Marqueur
Unconjugated (5)- (1)
| Numéro de produit | Espèces | Système d'expression | Description du produit | Structure protéique | Pureté | Caractéristiques | Pré-commande/Commande |
|---|---|---|---|---|---|---|---|
HOT GMP-L18H16 |  Human | E. coli | GMP Human IL-18 Protein |  |  |  |  Ajouter au panier |
| Human | E. coli | Human IL-18 Protein, premium grade |  | | | Ajouter au panier | |
| Human | E. coli | Human IL-18 Protein, Research Grade |  | |  | Ajouter au panier | |
| Human | - | resDetect™ Human IL-18 ELISA Kit (Residue Testing) | Ajouter au panier | ||||
 Mouse | E. coli | Mouse IL-18 Protein, His Tag |  | | | Ajouter au panier | |
 Rhesus macaque | E. coli | Rhesus macaque IL-18 Protein, Tag Free (MALS & SPR verified) |  | |  | Ajouter au panier |
Quantité totale6
- 1
IL-18Contexte de la molécule
Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-γ (IFN-γ) production from T helper type 1 (Th1) cells and natural killer (NK) cells, particularly in the presence of IL-12. IL-18 also participates in the developmental regulation of Th1 cells and mediates Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for the treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. IL-18 exerts its biological functions by inducing heterodimerization of the two subunits of its receptor, IL-18Rα and IL-18Rβ. These subunits share structural homology with members of the IL-1 receptor superfamily.
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