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IL-33

IL-33 Overview

English NameInterleukin-33Approved Drugs0
Drugs in Clinical Trials10Target SynonymNuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523
Highest Development StagePhase 3 Clinical
English NameInterleukin-33
Target SynonymNuclear Factor For High Endothelial Venules，DVS27-Related Protein，IL1F11，IL33，Interleukin-1 family member 11，IL-1F11，Interleukin 33，Nuclear Factor From High Endothelial Venules，C9orf26，NF-HEV，Chromosome 9 Open Reading Frame 26 (NF-HEV)，Interleukin-1 Family， Member 11，NFEHEV，DVS27，IL-33，NFHEV，Interleukin-33，DKFZp586H0523
Approved Drugs0
Drugs in Clinical Trials10
Highest Development StagePhase 3 Clinical

IL-33 Product List

  • Product Category

    Protein (11)

  • Product Status

    Launched (11)

  • Species

    Human (6)Cynomolgus (3)Mouse (2)

  • Tag

    His Tag (6)His Tag & Avi Tag (5)

  • Conjugate

    Unconjugated (6)Biotin-labeled (5)

Total: 11
  • 1
  • 2

IL-33 Background

Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.

IL-33 Synonyms

IL33,DV27,C9ORF26,IL1F11,NFHEV,DKFZp586H0523,DVS27,NFEHEV,RP11-575C20.2

Product Reviews

  • 1***62019-09-26
    1People Like
    Human IL-33 Protein, His Tag (HPLC verified)
    I used this protein to explore and establish experimental methods to do antibody screening. The experimental methods that I used include Elisa, flow cytometry, octet determination of antibody binding and competition experiments. The protein works well, the experiments results met my expectations. I buy ACRO's protein frequently.
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