NKp46

NKp46 Informations sur la molécule

Nom anglais	Natural cytotoxicity triggering receptor 1	Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3	Alias de la cible	NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335
Phase de R&D la plus avancée	Phase 2 Clinical

Nom anglais	Natural cytotoxicity triggering receptor 1
Alias de la cible	NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335
Nombre de médicaments commercialisés	0
Nombre de médicaments cliniques	3
Phase de R&D la plus avancée	Phase 2 Clinical

NKp46 Liste de produits

Attribut
Protein (16)Cell (2)Antibody (1)
Bibliothèque de produits
En ligne (19)
Espèces
Human (12)Cynomolgus (3)Mouse (4)
Étiquette
Fc Tag (4)His Tag (6)Llama IgG Fc Tag (2)Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)- (2)Tag Free (1)
Marqueur
Unconjugated (10)Biotin-labeled (5)- (2)PE Labeled (1)FITC Labeled (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT NC1-H52H4	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT NC1-H52H6	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, His Tag	Ajouter au panier
HOT NK6-H82E2	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, His Tag, ultra sensitivity (primary amine labeling)	Ajouter au panier
HOT NP6-H82H3	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, His,Avitag™, premium grade	Ajouter au panier
CHEK-ATP153	Human	HEK293	HEK293/Human NKp46 Stable Cell Line	Ajouter au panier
NC1-H5255	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Llama IgG2b Fc Tag, low endotoxin	Ajouter au panier
NC1-H5257	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag, premium grade	Ajouter au panier
NC1-H5258	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag	Ajouter au panier
NC1-H5259	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag	Ajouter au panier
NC1-H82F9	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, Fc,Avitag™, premium grade	Ajouter au panier

Quantité totale19

NKp46Contexte de la molécule

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

NKp46Alias de la molécule

NCR1,LY94,CD335,NK-p46,hNKp46

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
NY-303	NY-303	Phase 2 Clinical	NAYA Biosciences Inc	Carcinoma, Hepatocellular; Solid tumours	Details
IPH-6501	IPH-6501; IPH-65	Phase 2 Clinical	Innate Pharma SA	Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms	Details
SAR-443579	SAR-443579; SAR443579; SAR'579; IPH6101; IPH-6101	Phase 1 Clinical	Sanofi	Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematologic Diseases; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details