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Page d'accueilToutes les moléculesPTK7
PTK7
PTK7 Informations sur la molécule
| Nom anglais | Protein-tyrosine kinase 7 | Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 8 | Alias de la cible | Colon carcinoma kinase 4，Inactive tyrosine-protein kinase 7，Tyrosine-protein kinase-like 7，CCK-4，PTK7，Protein Tyrosine Kinase 7 (Inactive)，Pseudo Tyrosine Kinase Receptor 7，PTK7 Protein Tyrosine Kinase 7，CCK4，Protein-Tyrosine Kinase 7，Protein Tyrosine Kinase 7 |
| Phase de R&D la plus avancée | Phase 2 Clinical | ||
| Nom anglais | Protein-tyrosine kinase 7 |
| Alias de la cible | Colon carcinoma kinase 4，Inactive tyrosine-protein kinase 7，Tyrosine-protein kinase-like 7，CCK-4，PTK7，Protein Tyrosine Kinase 7 (Inactive)，Pseudo Tyrosine Kinase Receptor 7，PTK7 Protein Tyrosine Kinase 7，CCK4，Protein-Tyrosine Kinase 7，Protein Tyrosine Kinase 7 |
| Nombre de médicaments commercialisés | 0 |
| Nombre de médicaments cliniques | 8 |
| Phase de R&D la plus avancée | Phase 2 Clinical |
PTK7 Liste de produits
- Attribut
Protein (11)Cell (1)Antibody (1)
- Bibliothèque de produits
En ligne (13)
- Espèces
Human (5)Mouse (3)Rabbit (2)Cynomolgus / Rhesus macaque (1)Rat (2)
- Étiquette
His Tag (5)His Tag & Avi Tag (2)Fc Tag (3)Fc Tag & Avi Tag (1)- (2)
- Marqueur
Unconjugated (9)Biotin-labeled (3)- (1)
Ajouter au panier
Quantité totale13
- 1
- 2
PTK7Contexte de la molécule
PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
PTK7Alias de la molécule
PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Informations sur les médicaments cliniques
| Nom anglais | Code de recherche | Phase de R&D | Entreprise | Indication | Essai clinique |
|---|---|---|---|---|---|
| SKB-518 | SKB518; SKB-518 | Phase 2 Clinical | Sichuan Kelun-Biotech Biopharmaceutical Co Ltd | Genital Neoplasms, Female; Lung Neoplasms; Neoplasms; Solid tumours | Details |
| Cofetuzumab Pelidotin | PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 | Phase 1 Clinical | Abbvie Inc, Stemcentrx Inc | Carcinoma, Non-Small-Cell Lung; Neoplasms | Details |
| 68Ga-Sgc8 | Phase 1 Clinical | The First Affiliated Hospital of Air Force Medical University | Colorectal Neoplasms | Details | |
| PTK7 ADC (Eli Lilly and Company) | Phase 1 Clinical | Eli Lilly And Company | Neoplasms | Details | |
| KIVU-107 | KIVU-107 | Phase 1 Clinical | Kivu Bioscience Inc | Solid tumours | Details |
| LY-4175408 | LY4175408; LY-4175408 | Phase 1 Clinical | Eli Lilly And Company | Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Neoplasm Metastasis; Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms | Details |
| IDE-034 | BCG034; IDE034; IDE-034 | Phase 1 Clinical | Colorectal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Solid tumours | Details | |
| DAY-301 | DAY301; DAY-301; MTX-13; CB-002 | Phase 1 Clinical | Shanghai Mycos Biomedicine Co Ltd | Solid tumours | Details |
Avis sur les produits
1***62022-08-09
0Mettre un likeValidated by SPR, measured monovalent affinity, anti-human FC chip, loaded diluted antibody, added diluted Folate R, His tag, with the affinity constant of 4 nM.
- Informations sur la molécule
- Liste de produits
- Avis sur les produits
- Informations sur les médicaments cliniques
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