Transferrin R

Transferrin R Informations sur la molécule

Nom anglais	Transferrin receptor protein 1	Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	15	Alias de la cible	TFRC，T9，sTfR，Transferrin receptor protein 1，TR，Transferrin Receptor，P90，Transferrin Receptor (P90， CD71)，CD71 Antigen，IMD46，CD71，TfR1，Trfr，TfR
Phase de R&D la plus avancée	Approved

Nom anglais	Transferrin receptor protein 1
Alias de la cible	TFRC，T9，sTfR，Transferrin receptor protein 1，TR，Transferrin Receptor，P90，Transferrin Receptor (P90， CD71)，CD71 Antigen，IMD46，CD71，TfR1，Trfr，TfR
Nombre de médicaments commercialisés	1
Nombre de médicaments cliniques	15
Phase de R&D la plus avancée	Approved

Transferrin R Liste de produits

Attribut
Protein (16)Cell (1)
Bibliothèque de produits
En ligne (17)
Espèces
Human (7)Cynomolgus (4)Mouse (4)Rat (2)
Étiquette
His Tag (7)His Tag & Avi Tag (4)Fc Tag (3)Tag Free (2)Fc Tag & Avi Tag (1)
Marqueur
Unconjugated (8)Biotin-labeled (8)- (1)

Numéro de produit	Espèces	Système d'expression	Description du produit	Pré-commande/Commande
HOT CD1-H5243	Human	HEK293	Human Transferrin R / CD71 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT TFR-H5264	Human	HEK293	Human Transferrin R / CD71 Protein, Fc Tag, low endotoxin (MALS verified)	Ajouter au panier
HOT TFR-H82E5	Human	HEK293	Biotinylated Human Transferrin R / CD71 Protein, Avitag™,His Tag (MALS verified)	Ajouter au panier
HOT TFR-M8249	Mouse	HEK293	Biotinylated Mouse Transferrin R / CD71 Protein, His Tag, ultra sensitivity (primary amine labeling) (MALS verified)	Ajouter au panier
HOT TFR-C524a	Cynomolgus	HEK293	Cynomoguls / Rhesus macaque Transferrin R / CD71 Protein, His Tag, low endotoxin (MALS verified)	Ajouter au panier
CHEK-ATP089	Human	HEK293	HEK293/Human Transferrin R Stable Cell Line	Ajouter au panier
TFR-H5213	Human	HEK293	Human Transferrin R / CD71 Protein, Tag Free, low endotoxin (MALS verified)	Ajouter au panier
TFR-H8243	Human	HEK293	Biotinylated Human Transferrin R / CD71 Protein, His Tag, ultra sensitivity (primary amine labeling) (MALS verified)	Ajouter au panier
TFR-H82F3	Human	HEK293	Biotinylated Human Transferrin R / CD71 Protein, Fc,Avitag™	Ajouter au panier
TFR-M524b	Mouse	HEK293	Mouse Transferrin R / CD71 Protein, His Tag (MALS verified)	Ajouter au panier

Quantité totale17

Transferrin RContexte de la molécule

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Transferrin RAlias de la molécule

CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

Informations sur les médicaments cliniques

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Indication	Essai clinique
Human apotransferrin (Sanquin Blood Supply Foundation)		Phase 3 Clinical	Sanquin Plasma Products Bv	beta-Thalassemia; Iron Metabolism Disorders	Details
Delpacibart braxlosiran	AOC1020	Phase 3 Clinical	Avidity Biosciences Inc	Foot-and-Mouth Disease; Muscular Dystrophies; Muscular Dystrophy, Facioscapulohumeral	Details
Delpacibart eteddesiran	AOC-1001; AOC 1001	Phase 3 Clinical	Avidity Biosciences Inc	Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System; Muscular Atrophy; Muscular Diseases; Muscular Disorders, Atrophic; Muscular Dystrophies; Musculoskeletal Diseases; Myotonia; Myotonic Disorders; Myotonic Dystrophy; Nervous System Diseases; Neurodegenerative Diseases; Neuromuscular Diseases	Details
Trontinemab	RO-7126209; RG-6102	Phase 3 Clinical	F. Hoffmann-La Roche Ltd	Alzheimer Disease	Details
CX-2029	ABBV-2029; ABBV-CX-2029; CX-2029	Phase 2 Clinical	Abbvie Inc, Cytomx Therapeutics Inc	Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Head and Neck Neoplasms; Lymphoma, Large B-Cell, Diffuse; Solid tumours	Details
Zeleciment rostudirsen	DYNE251	Phase 2 Clinical	Dyne Therapeutics Inc	Muscular Dystrophy, Duchenne	Details
AOC-1044	AOC-1044; AOC 1044	Phase 2 Clinical	Avidity Biosciences Inc	Muscular Dystrophy, Duchenne	Details
JR-446	JR-446	Phase 2 Clinical	Jcr Pharmaceuticals Co Ltd, Medipal Holdings Corp	Mucopolysaccharidosis III	Details
JR-441	JR-441	Phase 2 Clinical	Jcr Pharmaceuticals Co Ltd	Mucopolysaccharidosis III	Details
Lepunafusp alfa	JR-171	Phase 2 Clinical	Jcr Pharmaceuticals Co Ltd	Mucopolysaccharidosis I	Details
PPMX-T003	PPMX-T003	Phase 2 Clinical	Perseus Proteomics Inc	Leukemia; Polycythemia Vera	Details
INA-03	INA03	Phase 1 Clinical	Inatherys	Leukemia; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details
PRX012-TfR	PRX012-TfR	Phase 1 Clinical	Prothena	Alzheimer Disease	Details
KK-2260	KK2260; KK-2260	Phase 1 Clinical	Kyowa Kirin Co Ltd	Esophageal Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck	Details
ABX-1100	ABX-1100	Phase 1 Clinical	Aro Biotherapeutics Co	Glycogen Storage Disease Type II	Details

Informations sur les médicaments commercialisés

Nom anglais	Code de recherche	Phase de R&D	Entreprise	Plus ancien nom de marque	Pays d'approbation le plus ancien	Indication la plus ancienne	Société d'approbation la plus ancienne	Date d'approbation la plus ancienne	Indication	Essai clinique
Pabinafusp alfa	JR-141	Approved	Jcr Pharmaceuticals Co Ltd		Japan	Mucopolysaccharidosis II	Jcr Pharmaceuticals Co Ltd	2021-03-23	Mucopolysaccharidosis II	Details

Avis sur les produits

***a2026-05-29
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Mouse Transferrin R Protein, Fc Tag (MALS verified)
Was purchased for use in BLI, both for immobilization onto human fc binding sensors and as analyte with a biotin-labeled TfR-targeting nanobody on streptavidin. Retested for use after 1.5 years storage at -80 and still had full functional activity.
S*** 2025-11-18
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Biotinylated Mouse Transferrin R / CD71 Protein, Avitag™,His Tag (MALS verified)
Used this material as a captured ligand in routine SPR testing on a Biacore. Material is clean, consistent, and easy to work with, and can be used to generate quality data
ZZ2022-10-11
0Mettre un like
Human Transferrin R / CD71 Protein, His Tag, low endotoxin (MALS verified)
We needed this product for our antibody research. ACRO managed to get it to us much faster than we expected, which made our research work very accurate. cd71 is a potential new target in human leukemia and lymphoma cases. cd71 /TFRC / TfR has been shown to interact with GABARAP and HFE. I am very pleased with the product and the quick technical support.