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Détails du produit
Source
Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) is a mouse monoclonal antibody recombinantly expressed in HEK293 cells.
Antibody Type
Recombinant Monoclonal
Clone
11C4C1
Isotype
Mouse IgG2a, Kappa
Host Species
Mouse
Reactivity
Human
Immunogen
mRNA-CCR8
Specificity
Specifically recognizes Human CCR8 Protein.
Purification
Protein A purified / Protein G purified.
Aggregation
Less than 10%, as determined by SEC-MALS.
Concentration
Please refer to the Certificate of Analysis (CoA).
Form
Lyophilized
Formulation
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
Reconstitution
Please refer to the Certificate of Analysis (CoA) for specific instructions.
Shipping
Lyophilized product is shipped at ambient temperature.
Storage
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 12 months under sterile conditions after reconstitution.
Notices
Product Specific Notices: For research use only.
ACRO Quality Management System
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Affichage des données
Bioactivity-ELISA
Immobilized Human CCR8 Protein (VLP) (Cat. No. CC8-H52P5) at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) with a linear range of 0.08-3 ng/mL. Virus-Like Particle (VLP) Protein Isotype Control (Cat. No. VLP-N5213) is verified not recoginized by Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) in low concentration (QC tested).
Protocol
Bioactivity-FACS
1e6 of HEK293/Human CCR8 Stable Cells Line were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) and isotype control antibody respectively, washed and then followed by PE anti-mouse IgG2a antibody and analyzed with FACS (QC tested).
Protocol
1e6 of HEK293/Human CCR8 Stable Cells Line (Cat. No. CHEK-ATP140) were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CCR8 Antibody, Mouse IgG2a (11C4C1) (Cat. No. CC8-MY2406) and isotype control antibody (Cat. No. DNP-M487) respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). PE signal was used to evaluate the binding activity (QC tested).
Protocol
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Introduction de fond
Progrès de frontière
Progrès du développement médicamenteux- Nom anglais：
C-C chemokine receptor type 8
- Catégorie：
- Nombre de médicaments répertoriés：
0 Détails
- Nombre de médicaments cliniques：
20 Détails
- Étape de développement la plus élevée：
Phase 3 Clinical
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