Anti-Rabies virus glycoprotein G Antibody, Mouse IgG1 (523-11) (MALS verified)

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Cat. No. / Size
Price
Qty
RAG-M305-100ug
$450.00
RAG-M305-1mg (500ug X 2)
$3255.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Anti-Rabies virus glycoprotein G Antibody, Mouse IgG1 (523-11) is a mouse monoclonal antibody recombinantly expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    523-11

  • Isotype

    Mouse IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Rabies virus glycoprotein G

  • Specificity

    This antibody specifically binds to the glycoprotein of Rabies virus.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Glycoprotein/G Protein (RABV) ELISA

    Immobilized Rabies virus Glycoprotein, His Tag (Cat. No. RAG-V55H5) at 1 μg/mL (100 μL/well) can bind Mouse Glycoprotein G Antibody, Mouse IgG1 (523-11) (Cat. No. RAG-M305) with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

Customer Reviews
Writing Reviews

  • 1***52022-08-10
    Likes
    When we first purchased ACRO's rabies G protein, our aim was to use it as a replacement for imported test kits. We have been trying to use it for testing post-exemption sera from animals, but it has always been paired with other brands of rabies antibodies for the development of analytical methods and evaluation of immunization effectiveness. Now shown by the data report, this RAG-M305 from ACRO has much better results compared with the previous antibodies used in our laboratory.

Background

Rabies virus (RABV), scientific name Rabies lyssavirus, is a deadly neurotropic virus that causes rabies in humans and animals. Rabies virus has an extremely wide host range and its transmission most often occur through the saliva of animals. Without intervention prior to disease progression, rabies has the highest case fatality of any infectious disease. RABV contains a single-stranded negative-sense RNA genome that encodes five structural proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and RNA-dependent RNA polymerase (L). Among these viral proteins, the RABV glycoprotein (RABV-G) is a pivotal player mediating virus entry and the major target of neutralizing antibodies, thus a key factor for vaccine and drug design.

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  • Performance Data
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  • Background