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Human Cadherin-10 / CDH10 Protein, His Tag, low endotoxin

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Numéro de produit/spécification
Prix
Qté
CA0-H52H5-100ug
$395.00
CA0-H52H5-1mg
$2615.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Synonyms

    Cadherin-10, CDH10, T2-cadherin

  • Source

    Human Cadherin-10, His Tag (CA0-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 55 - Ala 613 (Accession # Q9Y6N8-1).

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  • Molecular Characterization

    Cadherin-10 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 64.2 kDa. The protein migrates as 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • SDS-PAGE

    Cadherin-10 SDS-PAGE

    Human Cadherin-10, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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Introduction de fond

Cadherins are a large family of cell –cell adhesion molecules involved in inter-cellular adhesion in a wide variety of cell types. In the nervous system, cadherins are known to be crucial to all stages of development, including the early separation of the neural tube from the ectoderm, the segregation of neurones and axons, and the formation of synapses. These molecules mediate calcium ion-dependent, homotypic primers designed using two highly conserved amino acid sequences in the cytoplasmic domain. One of the cadherins identified was cadherin-10. Cadherin-10 was first partially cloned from human brain, but its mR has also been shown to be present in mouse thymus (designated T2-cadherin), mouse testis, and in the developing brain and eye of mouse, rat, and chick.

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