FITC-Labeled Human CD37 Protein, Fc Tag

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Cat. No. / Size
Price
Qty
CD7-HF26x-25ug
$330.00
CD7-HF26x-200ug
$2245.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    CD37, Tspan-26, TSPAN26

  • Source

    FITC-Labeled Human CD37, Fc Tag (CD7-HF26x) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1). It is the FITC labeled form of Human CD37, Fc Tag (Cat. No. CD7-H525a).

    Predicted N-terminus: Arg 112

    Request for sequence
  • Molecular Characterization

    CD37 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 41.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Conjugate

    FITC

    Excitation source: 488 nm spectral line, argon-ion laser

    Excitation Wavelength: 488 nm

    Emission Wavelength: 535 nm

  • Labeling

    The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with FITC using standard chemical labeling method. The residual FITC is removed by molecular sieve treatment during purification process.

  • Protein Ratio

    The FITC to protein molar ratio is 1.5-3.5.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CD37 SDS-PAGE

    FITC-Labeled Human CD37, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

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Background

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

Recent Advances

 
Drug Development Progress
  • English Name:

    Leukocyte antigen CD37

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    8 Details

  • Highest Development Stage:

    Phase 2 Clinical

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