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Biotinylated Influenza A virus (A/Victoria/4897/2022) NA (H1N1) Protein, Avitag™,His Tag

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Numéro de produit/spécification
Prix
Qté
NEE-V82Q3-25ug
$380.00
NEE-V82Q3-200ug
$1520.00
ETA of in-stock products:2 business days
Total des articles Montant du produit$ 0

Détails du produit

  • Synonyms

    NA, Neuraminidase

  • Source

    Biotinylated Influenza A virus (A/Victoria/4897/2022) NA (H1N1) Protein, Avitag,His Tag (NEE-V82Q3) is expressed from human 293 cells (HEK293). It contains AA Val 80 - Asn 469 (Accession # EPI_ISL_17102775, GISAID).

    Predicted N-terminus: Gly

    Request for sequence

  • Molecular Characterization

    Neuraminidase (NA) Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a polyhistidine tag.

    The protein has a calculated MW of 52.6 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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  • SDS-PAGE

    Neuraminidase (NA) SDS-PAGE

    Biotinylated Influenza A virus (A/Victoria/4897/2022) NA (H1N1) Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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Introduction de fond

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

Progrès de frontière

 
Progrès du développement médicamenteux
  • Nom anglais:

    Neuraminidase

  • Catégorie:

  • Nombre de médicaments répertoriés:

    4 Détails

  • Nombre de médicaments cliniques:

    10 Détails

  • Étape de développement la plus élevée:

    Approved

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