Détails du produit
Synonyms
OX40L, TNFSF4, CD252, Glycoprotein Gp34, TXGP1, CD134 ligand, CD134L
Source
Cynomolgus / Rhesus macaque OX40 Ligand, Mouse IgG2a Fc Tag (OXL-R5259) is expressed from human 293 cells (HEK293). It contains AA Gln 51 - Leu 183 (Accession # F7FL80-1). In the region Gln 51 - Leu 183, the amino acid sequences of Cynomolgus and Rhesus macaque OX40 Ligand are identical.
Predicted N-terminus: Glu
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a mouse IgG2a Fc tag at the N-terminus.
The protein has a calculated MW of 42.5 kDa. The protein migrates as 47-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
The protein is designed as a trimer.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Affichage des données
SDS-PAGE

Cynomolgus / Rhesus macaque OX40 Ligand, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
SEC-MALS

The purity of Cynomolgus / Rhesus macaque OX40 Ligand, Mouse IgG2a Fc Tag (Cat. No. OXL-R5259) is more than 85% and the molecular weight of this protein is around 270-300 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Cynomolgus / Rhesus macaque OX40, His Tag (Cat. No. OX0-C5220) at 2 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque OX40 Ligand, Mouse IgG2a Fc Tag (Cat. No. OXL-R5259) with a linear range of 0.1-3 ng/mL (QC tested).
Protocol
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Introduction de fond
Progrès de frontière
- Nom anglais:
Tumor necrosis factor ligand superfamily member 4
- Catégorie:
- Nombre de médicaments répertoriés:
0 Détails
- Nombre de médicaments cliniques:
13 Détails
- Étape de développement la plus élevée:
Phase 3 Clinical



















