Human STEAP2 Full Length Protein, Flag Tag (Nanodisc-pro)

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Cat. No. / Size
Price
Qty
ST2-H55C3-20ug
$750.00
ST2-H55C3-100ug
$1500.00
ST2-H55C3-500ug
$4800.00
ETA of in-stock products:2 business days

Product Details

  • Application

    1. Cell based assay (FACS or functional assay)
    2. Affinity testing (SPR / BLI)
    3. Screening (ELISA)
  • Synonyms

    STEAP2

  • Source

    Nanodisc-pro Human STEAP2 Full Length Protein, Flag Tag (ST2-H55C3) is expressed from Baculovirus-Insect cells. It contains AA Glu 2 - Met 490 (Accession # Q8NFT2-1).

    Predicted N-terminus: Met

    Request for sequence
  • Molecular Characterization

    STEAP2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a flag tag at the C-terminus.

    The protein has a calculated MW of 57.7 kDa.

    *The isotype control of empty/mock nanodisc (Cat. No. APO-H5143) is sold separately and not included in protein, you can follow the link for product information.

    1. Structure

      Nanodisc-pro membrane protein is wrapped by a piece of cell membrane and scaffold, the info of scaffold can be found in above red text "isotope type control...".

    2. Synthesis Process

      Nanodisc-pro membrane protein extraction is a gentle, non-disruptive process that directly isolates full-length transmembrane proteins together with their surrounding native phospholipids from cellular membranes, without breaking or disturbing the original membrane structure. This preserves the membrane protein's natural conformational landscape and native lipid environment, yielding stable nanodisc that retain cellular phospholipids, with fully preserved biological activity—making them ideal for cell-based assays such as FACS and binding assays in antibody discovery and screening (ELISA), etc.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     STEAP2 ELISA

    Immobilized Human STEAP2 Full Length Protein, Flag Tag (Cat. No. ST2-H55C3) at 5 μg/mL (100 μL/well) can bind Anti-STEAP2 Antibody with a linear range of 0.078-5 μg/mL (QC tested).

    Protocol

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Background

A member of the STEAP metalloreductase family involved in iron and copper homeostasis. STEAP2 is highly expressed in prostate cancer and contributes to tumor cell proliferation and invasiveness. Its transmembrane topology and tumor-selective profile support its utility as an immunotherapy target for prostate carcinoma.

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