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Your Position: Accueil > Protein > EMMPRIN > CD7-H5259

Human EMMPRIN / CD147 Protein, Fc Tag

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  • Synonym
    Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF
  • Source
    Human EMMPRIN, Fc Tag(CD7-H5259) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - His 205 (Accession # NP_940991.1).
    Predicted N-terminus: Ala 22
  • Molecular Characterization
    EMMPRIN Structure

    This protein carries a human IgG1 Fc tag at the C-terminus

    The protein has a calculated MW of 46.3 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
EMMPRIN SDS-PAGE

Human EMMPRIN, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
 EMMPRIN ELISA

Immobilized Human EMMPRIN, Fc Tag (Cat. No. CD7-H5259) at 1 μg/mL (100 μL/well) can bind Anti-EMMPRIN Antibody, Mouse IgG1 with a linear range of 0.2-4 ng/mL (QC tested).

  • Background
    CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Price(EUR) : €260.00

Price(EUR) : €1620.00

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Drug Development Status

  • Number of Launched Drugs:1 Details
  • Number of Drugs in Clinical Trials:5 Details
  • Latest Research Phase:Approved

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