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Your Position: Accueil > Antibody > Olig2 > OL2-S456

Polyclonal Olig2 Antibody, Rabbit IgG

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  • Source
    Rabbit
  • Isotype

    Rabbit IgG

  • Conjugate

    Unconjugated

  • Specificity

    This product is a specific antibody specifically reacts with Olig2.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in undefined.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at 4°C. Store at -20/4°C for months and -80°C for years. Avoid freeze/thaw cycle.
Immunostaining
 Olig2 IMMUNOSTAINING

2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling Olig2 (Red) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

 Olig2 IMMUNOSTAINING

3D organoid staining: Immunofluorescent staining (4x or 10X) of cerebral organoid-(CIPO-BWL001K) labeling Olig2 (Green) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain. TUJ1 (red) is a neural differentiation marker commonly used to label neural processes.

  • Background
    The oligodendrocyte transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor which is highly expressed in the oligodendrocyte-lineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.
  • Clinical and Translational Updates

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