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Your Position: Accueil > Serum Albumin

Serum Albumin

Brief Information

Name:Serum albumin
Target Synonym:PRO1341,PRO0883,ALB,HSA,PRO0903,Albumin,Serum Albumin
Number of Launched Drugs:17
Number of Drugs in Clinical Trials:14
Lastest Research Phase:Approved

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Part of Bioactivity data

RSA-R52H1-SPR
 Serum Albumin SPR

Rat Serum Albumin, His Tag (Cat. No. RSA-R52H1) immobilized on CM5 Chip can bind Rat FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (Cat. No. FCM-R5287) with an affinity constant of 4.98 μM as determined in a SPR assay (Biacore 8K) (QC tested).

MSA-M82E4-SPR
 Serum Albumin SPR

Biotinylated Mouse Serum Albumin, His,Avitag (Cat. No. MSA-M82E4) immobilized on SA Chip can bind Mouse FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCM-M52W8) with an affinity constant of 377 nM as determined in a SPR assay (Biacore 8K) (QC tested).

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Synonym Name

ALB,Alb,Alb-1,Alb1,Serum albumin,FCGRT,HAS,MSA,RSA,CSA

Background

serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Human albumin (Hebei Da'an Pharmaceutical) Approved Hebei Daan Pharmaceutical Co Ltd Mainland China Respiratory Distress Syndrome, Adult; Fibrosis; Shock, Hemorrhagic Hebei Daan Pharmaceutical Co Ltd 2002-01-31 Fibrosis; Respiratory Distress Syndrome, Adult; Shock, Hemorrhagic Details
20% Human albumin (Hemarus Therapeutics) Approved Hemarus Therapeutics Hemalb India Respiratory Distress Syndrome, Adult; Nephrotic Syndrome; Hypoalbuminemia; Hypovolemia Hemarus Therapeutics 2015-08-01 Hypovolemia; Respiratory Distress Syndrome, Adult; Hypoalbuminemia; Nephrotic Syndrome Details
Human albumin (Guizhou Taibang Biological Products) Approved Guizhou Taibang Biological Products Co Ltd Mainland China Respiratory Distress Syndrome, Adult; Fibrosis; Shock, Hemorrhagic Guizhou Taibang Biological Products Co Ltd 1998-01-01 Fibrosis; Respiratory Distress Syndrome, Adult; Shock, Hemorrhagic Details
Ozoralizumab PF-5230896; ATN-103; PF-05230896; TS-152 Approved Ablynx Nv ナノゾラ, Nanozora Japan Arthritis, Rheumatoid Taisho Pharmaceutical Co Ltd 2022-09-26 Arthritis, Rheumatoid Details
Human albumin (Hualan Biological Engineering) Approved Hualan Genetic Engineering Co Ltd Mainland China Hemorrhage; Hypovolemia; Anemia, Hemolytic, Autoimmune; Hypoalbuminemia Hualan Genetic Engineering Co Ltd 1995-01-01 Hypovolemia; Hemorrhage; Anemia, Hemolytic, Autoimmune; Hypoalbuminemia Details
Human Albumin(Guangdong Danxia) Approved Guangdong Danxia Biological Pharmaceutical Co Ltd Mainland China Hypovolemia Guangdong Danxia Biological Pharmaceutical Co Ltd 2012-10-30 Hypovolemia Details
Human Albumin(Anhui Da'An) Approved Tonrol Bio-Pharmaceutical Co Ltd Mainland China Tonrol Bio-Pharmaceutical Co Ltd 2002-01-31 Details
Human Albumin(Huhan Nanyue) Approved Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd Mainland China Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd 1994-01-01 Details
Human albumin(Tonrol Bio-Pharmaceutical) Approved Tonrol Bio-Pharmaceutical Co Ltd Mainland China Hypovolemia Tonrol Bio-Pharmaceutical Co Ltd 1996-01-01 Hypovolemia Details
Human Albumin (SK Plasma) Approved Sk Plasma Co Ltd Mainland China Sk Plasma Co Ltd 2010-03-15 Details
Human Serum Albumin (Green Cross) Approved Green Cross China Biological Products Co Ltd Mainland China Hypovolemia Green Cross China Biological Products Co Ltd 1998-01-01 Hypovolemia Details
Albumin Human(Cis Bio International) Approved Cis Bio International Sa Pulmocis EU Cis Bio International Sa 2020-04-06 Details
Perfluoropropane human albumin microspheres(Hunan Jingda) Approved Hunan kangrun Pharmaceutical Co Ltd Mainland China Contrast agents Hunan kangrun Pharmaceutical Co Ltd 2008-10-13 Liver Diseases; Contrast agents Details
Albumin Human(Sanquin Plasma Products) Approved Sanquin Plasma Products Bv Details
Albumin Human (Biotest Pharma GmbH) Approved Biotest Pharma Gmbh Albiomin, Albiomin 5%, Albiomin 10% EU Biotest Pharma Gmbh 2008-12-18 Hypovolemia Details
Human albumin(Gailifu Pharmaceutical Technology) Approved Grifols Medical Consulting(Shanghai)Co Ltd Mainland China Shock, Hemorrhagic; Edema; Ascites; Pharmaceutical aids; Hypoproteinemia; Hyperbilirubinemia, Neonatal; Respiratory Distress Syndrome, Adult; Burns; Hypovolemia; Intracranial Hypertension Grifols Medical Consulting(Shanghai)Co Ltd 2012-01-01 Hypovolemia; Hypoproteinemia; Hyperbilirubinemia, Neonatal; Shock, Hemorrhagic; Ascites; Respiratory Distress Syndrome, Adult; Pharmaceutical aids; Burns; Intracranial Hypertension; Edema Details
Vialebex (LFB SA/Swedish Orphan Biovitrum AB) Approved Lfb Biotechnologies Sas, Swedish Orphan Biovitrum Ag France Hypotension; Shock null 2013-02-01 Hypotension; Shock Details
Human albumin (Hebei Da'an Pharmaceutical) Approved Hebei Daan Pharmaceutical Co Ltd Mainland China Respiratory Distress Syndrome, Adult; Fibrosis; Shock, Hemorrhagic Hebei Daan Pharmaceutical Co Ltd 2002-01-31 Fibrosis; Respiratory Distress Syndrome, Adult; Shock, Hemorrhagic Details
20% Human albumin (Hemarus Therapeutics) Approved Hemarus Therapeutics Hemalb India Respiratory Distress Syndrome, Adult; Nephrotic Syndrome; Hypoalbuminemia; Hypovolemia Hemarus Therapeutics 2015-08-01 Hypovolemia; Respiratory Distress Syndrome, Adult; Hypoalbuminemia; Nephrotic Syndrome Details
Human albumin (Guizhou Taibang Biological Products) Approved Guizhou Taibang Biological Products Co Ltd Mainland China Respiratory Distress Syndrome, Adult; Fibrosis; Shock, Hemorrhagic Guizhou Taibang Biological Products Co Ltd 1998-01-01 Fibrosis; Respiratory Distress Syndrome, Adult; Shock, Hemorrhagic Details
Ozoralizumab PF-5230896; ATN-103; PF-05230896; TS-152 Approved Ablynx Nv ナノゾラ, Nanozora Japan Arthritis, Rheumatoid Taisho Pharmaceutical Co Ltd 2022-09-26 Arthritis, Rheumatoid Details
Human albumin (Hualan Biological Engineering) Approved Hualan Genetic Engineering Co Ltd Mainland China Hemorrhage; Hypovolemia; Anemia, Hemolytic, Autoimmune; Hypoalbuminemia Hualan Genetic Engineering Co Ltd 1995-01-01 Hypovolemia; Hemorrhage; Anemia, Hemolytic, Autoimmune; Hypoalbuminemia Details
Human Albumin(Guangdong Danxia) Approved Guangdong Danxia Biological Pharmaceutical Co Ltd Mainland China Hypovolemia Guangdong Danxia Biological Pharmaceutical Co Ltd 2012-10-30 Hypovolemia Details
Human Albumin(Anhui Da'An) Approved Tonrol Bio-Pharmaceutical Co Ltd Mainland China Tonrol Bio-Pharmaceutical Co Ltd 2002-01-31 Details
Human Albumin(Huhan Nanyue) Approved Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd Mainland China Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd 1994-01-01 Details
Human albumin(Tonrol Bio-Pharmaceutical) Approved Tonrol Bio-Pharmaceutical Co Ltd Mainland China Hypovolemia Tonrol Bio-Pharmaceutical Co Ltd 1996-01-01 Hypovolemia Details
Human Albumin (SK Plasma) Approved Sk Plasma Co Ltd Mainland China Sk Plasma Co Ltd 2010-03-15 Details
Human Serum Albumin (Green Cross) Approved Green Cross China Biological Products Co Ltd Mainland China Hypovolemia Green Cross China Biological Products Co Ltd 1998-01-01 Hypovolemia Details
Albumin Human(Cis Bio International) Approved Cis Bio International Sa Pulmocis EU Cis Bio International Sa 2020-04-06 Details
Perfluoropropane human albumin microspheres(Hunan Jingda) Approved Hunan kangrun Pharmaceutical Co Ltd Mainland China Contrast agents Hunan kangrun Pharmaceutical Co Ltd 2008-10-13 Liver Diseases; Contrast agents Details
Albumin Human(Sanquin Plasma Products) Approved Sanquin Plasma Products Bv Details
Albumin Human (Biotest Pharma GmbH) Approved Biotest Pharma Gmbh Albiomin, Albiomin 5%, Albiomin 10% EU Biotest Pharma Gmbh 2008-12-18 Hypovolemia Details
Human albumin(Gailifu Pharmaceutical Technology) Approved Grifols Medical Consulting(Shanghai)Co Ltd Mainland China Shock, Hemorrhagic; Edema; Ascites; Pharmaceutical aids; Hypoproteinemia; Hyperbilirubinemia, Neonatal; Respiratory Distress Syndrome, Adult; Burns; Hypovolemia; Intracranial Hypertension Grifols Medical Consulting(Shanghai)Co Ltd 2012-01-01 Hypovolemia; Hypoproteinemia; Hyperbilirubinemia, Neonatal; Shock, Hemorrhagic; Ascites; Respiratory Distress Syndrome, Adult; Pharmaceutical aids; Burns; Intracranial Hypertension; Edema Details
Vialebex (LFB SA/Swedish Orphan Biovitrum AB) Approved Lfb Biotechnologies Sas, Swedish Orphan Biovitrum Ag France Hypotension; Shock null 2013-02-01 Hypotension; Shock Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Gefurulimab TPP-2511; ALXN-1720; CON-9978 Phase 3 Clinical Alexion Pharmaceuticals Inc Myasthenia Gravis; Proteinuria Details
Izokibep IMG-020; IMG020; ABY-035; AFB-035 Phase 3 Clinical Affibody Ab Non-radiographic axial spondyloarthritis; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Hidradenitis Suppurativa; Uveitis; Plaque psoriasis Details
Albumin(King Edward Medical University) Phase 3 Clinical King Edward Medical University Burns Details
Hyperoncotic human albumin Phase 3 Clinical Manchester University Nhs Foundation Trust Shock, Septic; Sepsis; Shock Details
MK-6070 HPN-328; MK-6070 Phase 2 Clinical Harpoon Therapeutics Small Cell Lung Carcinoma Details
Human Albumin (European Foundation for Study of Chronic Liver Failure) Phase 2 Clinical European Foundation For Chronic Liver Failure Liver Cirrhosis Details
Human albumin (Baylor College of Medicine) Phase 2 Clinical Baylor College Of Medicine Ascites Details
Human albumin(Albimmune) Phase 2 Clinical Shock, Septic Details
Tarperprumig ALXN-1820 Phase 2 Clinical Alexion Pharmaceuticals Inc Anemia, Sickle Cell Details
ND-021 ND-021; NM21-1480; CS-2006; CS2006 Phase 1 Clinical Numab Therapeutics Ag, Cstone Pharmaceuticals Solid tumours; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
Albumin(Tianjin Huanhu Hospital) Phase 1 Clinical Tianjin Huanhu Hospital Hypoproteinemia; Stroke; Mesenteric Vascular Occlusion Details
Gefurulimab TPP-2511; ALXN-1720; CON-9978 Phase 3 Clinical Alexion Pharmaceuticals Inc Myasthenia Gravis; Proteinuria Details
Izokibep IMG-020; IMG020; ABY-035; AFB-035 Phase 3 Clinical Affibody Ab Non-radiographic axial spondyloarthritis; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Hidradenitis Suppurativa; Uveitis; Plaque psoriasis Details
Albumin(King Edward Medical University) Phase 3 Clinical King Edward Medical University Burns Details
Hyperoncotic human albumin Phase 3 Clinical Manchester University Nhs Foundation Trust Shock, Septic; Sepsis; Shock Details
MK-6070 HPN-328; MK-6070 Phase 2 Clinical Harpoon Therapeutics Small Cell Lung Carcinoma Details
Human Albumin (European Foundation for Study of Chronic Liver Failure) Phase 2 Clinical European Foundation For Chronic Liver Failure Liver Cirrhosis Details
Human albumin (Baylor College of Medicine) Phase 2 Clinical Baylor College Of Medicine Ascites Details
Human albumin(Albimmune) Phase 2 Clinical Shock, Septic Details
Tarperprumig ALXN-1820 Phase 2 Clinical Alexion Pharmaceuticals Inc Anemia, Sickle Cell Details
ND-021 ND-021; NM21-1480; CS-2006; CS2006 Phase 1 Clinical Numab Therapeutics Ag, Cstone Pharmaceuticals Solid tumours; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
Albumin(Tianjin Huanhu Hospital) Phase 1 Clinical Tianjin Huanhu Hospital Hypoproteinemia; Stroke; Mesenteric Vascular Occlusion Details

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