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Your Position: Accueil > MUC-17

MUC-17

Brief Information

Name:Mucin-17
Target Synonym:Small intestinal mucin-3,MUC-3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:IND

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
MU7-H52H3 Human Human MUC-17 Protein, His Tag
MU7-H52H3-structure
MU7-H52H3-sds
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Synonym Name

Mucin-17,MUC-17,MUC17,MUC-3,MUC3

Background

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

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