Acrobiosystems for English
icon_bulk_orderAchat groupé/Commande rapide
user
  1. Tableau de bord
  2. Mon profil
  3. Mon adresse
  4. Mes commandes
  5. Adhésion à Acro
Connexion Inscription
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
Il n'y a pas de produit dans le panier !
Mon panier|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Accueil > NOTCH3

NOTCH3

Brief Information

Name:Neurogenic locus notch homolog protein 3
Target Synonym:Neurogenic Locus Notch Homolog Protein 3,LMNS,Notch 3,NOTCH3,Notch (Drosophila) Homolog 3,Notch Homolog 3 (Drosophila),Notch Homolog 3,CADASIL1,CADASIL,CASIL,IMF2,Receptor, Notch3,Notch Receptor 3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

Product ListCompare or Buy

Product> Filter Results
Par statut du produit :
Par catégorie de produit :
Par espèce :
Par étiquette :
Par conjugaison :
Cat . Non Espèces Description du produit Structure Pureté Caractéristique
NO3-H5255 Human Human NOTCH3 Protein, Fc Tag
NO3-H5255-structure
NO3-H5255-sds
ACRO Quality

Part of Bioactivity data

NO3-H5255-MALS-HPLC
NOTCH3 ELISA

Immobilized Human NOTCH3, Fc Tag (Cat. No. NO3-H5255) at 1 μg/mL (100 μL/well) can bind Bispecific Antibody (NOTCH2 × NOTCH3) with a linear range of 2-20 ng/mL (QC tested).

Protocol

Synonym Name

Notch-3,NOTCH3

Background

Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs

Clinical and Translational Updates

    This web search service is supported by Google Inc.

    totop
    Call us
    Call us

    Germany+49 800 0826645

    United Kingdom+44 808 281 3436

    Netherlands+31 800 0224992

    Switzerland+41 800 040 012

    France+33 800 90 78 85

    Sweden+46 20 12 76 94

    Denmark+45 80 83 07 62

    Belgium+32 800 27 125

    Email
    E-Mail
    order@acrobiosystems.com
    Fax
    Fax
    +1 888-377-6111
    Address
    Address
    Lichtstrasse 35,4056 Basel, Switzerland
    linkedin twitter facebook youtube

    Laisser un message

    Copyright © 2017 ACROBiosystems. All Rights Reserved
    Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap