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TOP2A

Brief Information

Name:Topoisomerase (DNA) II alpha
Target Synonym:EC:5.6.2.2,EC 5.6.2.2,TOP2A,DNA topoisomerase 2-alpha,DNA topoisomerase II, alpha isozyme,DNA Topoisomerase II Alpha,Topoisomerase (DNA) II Alpha 170kDa,TOP2,DNA Topoisomerase (ATP-Hydrolyzing),DNA Topoisomerase II, 170 KD,EC 5.99.1.3,TP2A,DNA Gyrase
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Approved

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
TOA-H5117 Human Human TOP2A / TOP2 Protein, Tag Free
TOA-H5117-structure
TOA-H5117-sds
ACRO Quality

Synonym Name

TOP2A,TOP2,DNA topoisomerase 2-alpha,DNA topoisomerase II,alpha isozyme

Background

Clinical and Translational Updates

    Public Drug Information

    Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
    Etoposide phosphate BMY-40481 Approved Bristol-Myers Squibb Company Etopophos United States Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hodgkin Disease; Lymphoma, Non-Hodgkin; Multiple Myeloma; Testicular Neoplasms; Small Cell Lung Carcinoma Cheplapharm Arzneimittel Gmbh 1996-05-17 Lung Neoplasms; Breast Neoplasms; Neuroblastoma; Sarcoma, Ewing; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms, Plasma Cell; Testicular Neoplasms; Neoplasms, Gonadal Tissue; Lymphoma; Germinoma; Brain Neoplasms; Lymphoma, Non-Hodgkin; Burkitt Lymphoma; Thrombocytopenia; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms, Germ Cell and Embryonal; Neoplasm Metastasis; Myelodysplastic-Myeloproliferative Diseases; Hodgkin Disease; Leukemia; Solid tumours; Kidney Neoplasms; Neutropenia; Small Cell Lung Carcinoma; Plasmacytoma; Lymphoma, Large B-Cell, Diffuse; Myeloproliferative Disorders; Ovarian Neoplasms; Neoplasms; Myelodysplastic Syndromes; Lymphoma, Large-Cell, Immunoblastic; Multiple Myeloma; Central Nervous System Neoplasms; Adrenocortical Carcinoma; Lymphoma, Follicular; Sarcoma Details
    Etoposide phosphate BMY-40481 Approved Bristol-Myers Squibb Company Etopophos United States Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hodgkin Disease; Lymphoma, Non-Hodgkin; Multiple Myeloma; Testicular Neoplasms; Small Cell Lung Carcinoma Cheplapharm Arzneimittel Gmbh 1996-05-17 Lung Neoplasms; Breast Neoplasms; Neuroblastoma; Sarcoma, Ewing; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms, Plasma Cell; Testicular Neoplasms; Neoplasms, Gonadal Tissue; Lymphoma; Germinoma; Brain Neoplasms; Lymphoma, Non-Hodgkin; Burkitt Lymphoma; Thrombocytopenia; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms, Germ Cell and Embryonal; Neoplasm Metastasis; Myelodysplastic-Myeloproliferative Diseases; Hodgkin Disease; Leukemia; Solid tumours; Kidney Neoplasms; Neutropenia; Small Cell Lung Carcinoma; Plasmacytoma; Lymphoma, Large B-Cell, Diffuse; Myeloproliferative Disorders; Ovarian Neoplasms; Neoplasms; Myelodysplastic Syndromes; Lymphoma, Large-Cell, Immunoblastic; Multiple Myeloma; Central Nervous System Neoplasms; Adrenocortical Carcinoma; Lymphoma, Follicular; Sarcoma Details

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