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Your Position: Accueil > MASP3

MASP3

Brief Information

Name:Mannan-binding lectin serine protease 1
Target Synonym:Complement-activating component of Ra-reactive factor,Mannose-binding lectin-associated serine protease 1 (MASP-1),Mannose-binding protein-associated serine protease,Ra-reactive factor serine protease p100 (RaRF),Serine protease 5,MASP1,CRARF,PRSS5,Complement factor MASP-3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
MA3-M52H3 Mouse Mouse MASP3 Protein, His Tag (active enzyme, MALS verified)
MA3-M52H3-structure
MA3-M52H3-sds
MA3-H52H3 Human Human MASP3 (450-721) Protein, His Tag (active enzyme)
MA3-H52H3-structure
MA3-H52H3-sds
ACRO Quality

Part of Bioactivity data

MA3-M52H3-BLI
MASP3 MALS images

The purity of Mouse MASP3 Protein, His Tag (Cat. No. MA3-M52H3) is more than 90% and the molecular weight of this protein is around 30-45 kDa verified by SEC-MALS.

Synonym Name

MASP3, MASP1, CRARF1, RaRF

Background

MASP3 is a member of the MASP family. The MASP family proteins were firstdiscovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associatedserine proteases, but later, they were found to interact with ficolins, and later still, collectin-10and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includesnon-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectinpathway with haematologic malignancies and related infections are discussed.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
OMS-906 OMS-906 Phase 2 Clinical University Of Leicester, Medical Research Council, Helion Biotech APS Hemoglobinuria, Paroxysmal; Glomerulonephritis Details
OMS-906 OMS-906 Phase 2 Clinical University Of Leicester, Medical Research Council, Helion Biotech APS Hemoglobinuria, Paroxysmal; Glomerulonephritis Details

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