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Project Name | Modality | Therapeutic Area | Indications | Stage | Right Available |
CCR8 Humanized Antibody | Bispecific antibody | Oncology/Cancer | Solid Tumor | Preclinical | Global |
Cat . Non | Espèces | Description du produit | Structure | Pureté | Caractéristique |
---|---|---|---|---|---|
CC8-H52D7 | Human | Human CCR8 Protein, Flag,His Tag&Twin-Strep Tag (Nanodisc) | |||
CC8-H52D6 | Human | Human CCR8 Protein, Flag,His Tag&Twin-Strep Tag (Detergent) | |||
CHEK-ATP140 | Human | HEK293/Human CCR8 Stable Cell Line | |||
CC8-H52P4 | Human | Human CCR8 Full Length Protein (VLP) |
Expression analysis of human CCR8 on HEK293/Human CCR8 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human CCR8 Stable Cell Line or negative control cell using anti-human CCR8 antibody followed by staining with PE anti-human IgG antibody.
Anti-CCR8 captured on Protein A Chip can bind Human CCR8 Protein, Flag,His Tag&Twin-Strep Tag (Cat. No. CC8-H52D6) with an affinity constant of 63.8 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
BMS-986340 | BMS-986340 | Phase 2 Clinical | Eeig Bristol-Myers Squibb Manufacturing Company Bristol-Myers Squibb Srl | Ovarian Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
S-531011 | S-531011 | Phase 2 Clinical | Shionogi Inc | Solid tumours | Details |
LM-108 | LM-108 | Phase 2 Clinical | LaNova Medicines Ltd | Solid tumours | Details |
BAY-3375968 | BAY-3375968 | Phase 1 Clinical | Bayer AG | Solid tumours; Neoplasms | Details |
ICP-B05 | CM-369; ICPB05 | Phase 1 Clinical | Keymed Biosciences Co Ltd, InnoCare Pharma Ltd | Hematologic Neoplasms; Solid tumours | Details |
HBM-1022 | HBM-1022 | Phase 1 Clinical | Harbour Biomed | Neoplasms | Details |
JTX-1811 | JTX-1811; GS-1811 | Phase 1 Clinical | Jounce Therapeutics Inc | Solid tumours | Details |
SRF-114 | SRF-114 | Phase 1 Clinical | Surface Oncology Inc | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms | Details |
BGB-A3055 | BGB-A3055 | Phase 1 Clinical | Beigene Ltd | Solid tumours; Neoplasm Metastasis | Details |
ABBV-514 | ABBV-514 | Phase 1 Clinical | Abbvie Inc | Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung | Details |
IPG-7236 | IPG-7236; IPG-007 | Phase 1 Clinical | Nanjing Immunophage Biotech Co Ltd | Solid tumours; Breast Neoplasms; Dermatitis, Atopic | Details |
ZL-1218 | ZL-1218 | Phase 1 Clinical | Zai Lab (Shanghai) Co Ltd | Solid tumours; Neoplasms | Details |
BMS-986340 | BMS-986340 | Phase 2 Clinical | Eeig Bristol-Myers Squibb Manufacturing Company Bristol-Myers Squibb Srl | Ovarian Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
S-531011 | S-531011 | Phase 2 Clinical | Shionogi Inc | Solid tumours | Details |
LM-108 | LM-108 | Phase 2 Clinical | LaNova Medicines Ltd | Solid tumours | Details |
BAY-3375968 | BAY-3375968 | Phase 1 Clinical | Bayer AG | Solid tumours; Neoplasms | Details |
ICP-B05 | CM-369; ICPB05 | Phase 1 Clinical | Keymed Biosciences Co Ltd, InnoCare Pharma Ltd | Hematologic Neoplasms; Solid tumours | Details |
HBM-1022 | HBM-1022 | Phase 1 Clinical | Harbour Biomed | Neoplasms | Details |
JTX-1811 | JTX-1811; GS-1811 | Phase 1 Clinical | Jounce Therapeutics Inc | Solid tumours | Details |
SRF-114 | SRF-114 | Phase 1 Clinical | Surface Oncology Inc | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms | Details |
BGB-A3055 | BGB-A3055 | Phase 1 Clinical | Beigene Ltd | Solid tumours; Neoplasm Metastasis | Details |
ABBV-514 | ABBV-514 | Phase 1 Clinical | Abbvie Inc | Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung | Details |
IPG-7236 | IPG-7236; IPG-007 | Phase 1 Clinical | Nanjing Immunophage Biotech Co Ltd | Solid tumours; Breast Neoplasms; Dermatitis, Atopic | Details |
ZL-1218 | ZL-1218 | Phase 1 Clinical | Zai Lab (Shanghai) Co Ltd | Solid tumours; Neoplasms | Details |
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