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JAB1

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
JA1-H5553 Human Human JAB1 / COPS5 Protein, Fc Tag
JA1-H5553-structure
JA1-H5553-sds
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Synonym Name

JAB1

Background

Jab1, also known as CSN5, is a component of (COP9) signalosome complex (CSN) and reported to be involved in the regulation of cell proliferation, cell-cycle progression, and tumorigenesis. As a component of the COP9 signalosome complex, Jab1 could reciprocally regulate the stability and transcriptional activity of MED1 and might be a MED1 direct target gene mediating the aggressive phenotypes of HER2+tumors.

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