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FGF-6

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
FG6-H51H4 Human Human FGF-6 Protein, His Tag
FG6-H51H4-structure
FG6-H51H4-sds
ACRO Quality

Part of Bioactivity data

FG6-H51H4-SPR
 FGF-6 SPR

Human FGF-6 Protein, His Tag (Cat. No. FG6-H51H4) immobilized on CM5 Chip can bind Human FGF R1, His Tag (Cat. No. FG1-H5223) with an affinity constant of 45 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

FG6-H51H4-SPR
 FGF-6 SPR

Human FGF-6 Protein, His Tag (Cat. No. FG6-H51H4) immobilized on CM5 Chip can bind Human FGF R4, Fc Tag (Cat. No. FG4-H5253) with an affinity constant of 13.4 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Synonym Name

FGF-6,Fibroblast growth factor 6,HST-2,HBGF-6

Background

Fibroblast growth factor 6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.For instance, FGF-6 might involve in MSCs proliferation and chondrogenic differentiation. Additionally, FGF-6 were identified as oncogene products. FGF6 is found over expressed in prostatic intraepithelial neoplasia and prostate cancer and promotes the proliferation of the transformed prostatic epithelial cells.

Clinical and Translational Updates

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