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FGF-5

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
FG5-H51H3 Human Human FGF-5 Protein, His Tag (SPR verified)
FG5-H51H3-structure
FG5-H51H3-sds
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Part of Bioactivity data

FG5-H51H3-ELISA
FGF-5 SPR

Human FGF-5 Protein, His Tag (Cat. No. FG5-H51H3) captured on CM5 chip via anti-His antibody can bind Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) with an affinity constant of 63.3 nM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol

Synonym Name

FGF-5,Fibroblast growth factor 5,HBGF-5

Background

Fibroblast growth factor-5 (FGF5) is a member of the fibroblast growth factor (FGF) family and acts as a crucial regulator of hair growth and an oncogenic factor in several human cancers. Generally, Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Overexpression of FGF5 has been associated with prostate cancer, pancreatic cancer, breast cancer, renal cell carcinoma, etc. it was confirmed that FGF5 contributes to the malignant progression of human astrocytic brain tumors by both autocrine and paracrine effects.

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