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FGF-7

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Part of Bioactivity data

FG7-H5213-SPR
 FGF-7 SPR

Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) immobilized on CM5 Chip can bind Human FGF-7 Protein, premium grade (Cat. No. FG7-H5213) with an affinity constant of 521 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

FG7-H52H5-SPR
 FGF-7 SPR

Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) immobilized on CM5 Chip can bind Human FGF-7 Protein, His Tag (Cat. No. FG7-H52H5) with an affinity constant of 0.275 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Synonym Name

FGF-7,Fibroblast growth factor 7,HBGF-7,Keratinocyte growth factor,KGF

Background

Fibroblast growth factor (FGF) 7 (is also known as Keratinocyte growth factor (KGF)), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF7 and FGF10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.

Clinical and Translational Updates

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