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Your Position: Accueil > IL-20

IL-20

Brief Information

Name:Interleukin 20
Target Synonym:Interleukin-20,UNQ852/PRO1801,IL-20,IL20,Interleukin 20,Cytokine Zcyto10,ZCYTO10,Four Alpha Helix Cytokine,IL10D
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
IL0-H5243 Human Human IL-20 Protein, His Tag (MALS & SPR verified)
IL0-H5243-structure
IL0-H5243-sds
ACRO Quality

Part of Bioactivity data

IL0-H5243-SPR
IL-20 SPR

Human IL-20, His Tag (Cat. No. IL0-H5243) immobilized on CM5 Chip can bind Human IL-20 R alpha, Fc Tag (Cat. No. ILA-H525d) with an affinity constant of 4.42 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol
IL0-H5243-MALS-HPLC
IL-20 MALS images

The purity of Human IL-20, His Tag (Cat. No. IL0-H5243) is more than 90% and the molecular weight of this protein is around 16-24 kDa verified by SEC-MALS.

Synonym Name

interleukin-20,IL10D,IL-20,interleukin 20,Cytokine Zcyto10,ZCYTO10

Background

Interleukin-20 (IL-20) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. IL-20 induces STAT activation through two types of receptor complex, one of which it shares with IL-19, indicating that their biological activities may overlap. Both cytokines may play an important role in regulating the development and proper functioning of skin. IL-20 has also been shown to promote endothelial cell tube formation, suggesting that it may be involved in vascular vessel maturation and remodelling.

Clinical and Translational Updates

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