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IL-20 R alpha

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
ILA-H52H3 Human Human IL-20 R alpha Protein, His Tag (MALS & SPR verified)
ILA-H52H3-structure
ILA-H52H3-sds
ILA-H525d Human Human IL-20 R alpha Protein, Fc Tag (MALS verified)
ILA-H525d-structure
ILA-H525d-sds
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Part of Bioactivity data

ILA-H52H3-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human IL-20, His Tag (Cat. No. IL0-H5243) immobilized on CM5 Chip can bind Human IL-20 R alpha Protein, His Tag (Cat. No. ILA-H52H3) with an affinity constant of 3.31 μM as determined in a SPR assay (Biacore 8K) (QC tested).

ILA-H525d-SPR
 IL-20 R alpha SPR

Human IL-20, His Tag (Cat. No. IL0-H5243) immobilized on CM5 Chip can bind Human IL-20 R alpha, Fc Tag (Cat. No. ILA-H525d) with an affinity constant of 4.42 μM as determined in a SPR assay (Biacore 8K) (QC tested).

Synonym Name

Interleukin-20 receptor subunit alpha,IL-20 receptor subunit alpha,IL-20R-alpha,IL-20RA,Cytokine receptor class-II member 8,Cytokine receptor family 2 member 8,CRF2-8,IL-20R1,ZcytoR7

Background

The IL-20 receptor alpha subunit forms a functional heterodimer with the IL-20 beta subunit, and transduces ligand-binding at least in part through STAT3 activation.The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.

Clinical and Translational Updates

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