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CD171

Brief Information

Name:Neural cell adhesion molecule L1
Target Synonym:N-CAM-L1,NCAM-L1,CD171,MASA,SPG1,L1 Cell Adhesion Molecule,CD171 Antigen,MIC5,N-CAML1,Antigen Identified By Monoclonal Antibody R1,S10,CAML1,HSAS,HSAS1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
CD1-H52H4 Human Human CD171 Protein, His Tag (MALS verified)
CD1-H52H4-structure
CD1-H52H4-sds
ACRO Quality

Part of Bioactivity data

The purity of Human CD171, His Tag (Cat. No. CD1-H52H4) is more than 90% and the molecular weight of this protein is around 208-248 kDa verified by SEC-MALS.

Synonym Name

CD171/L1CAM

Background

L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising target for anti-cancer therapy.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
JCAR-023 JCAR-023 Phase 1 Clinical Seattle Children'S Hospital, Seattle Children'S Research Institute Neuroblastoma; Ganglioneuroblastoma Details
JCAR-023 JCAR-023 Phase 1 Clinical Seattle Children'S Hospital, Seattle Children'S Research Institute Neuroblastoma; Ganglioneuroblastoma Details

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