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HGF R

Brief Information

Name:Hepatocyte growth factor receptor
Target Synonym:EC 2.7.10,EC:2.7.10.1,HGF receptor,HGF/SF receptor,Hepatocyte growth factor receptor,Tyrosine-protein kinase Met,MET,SF receptor,Scatter factor receptor,MET Proto-Oncogene, Receptor Tyrosine Kinase,Proto-Oncogene C-Met,Met Proto-Oncogene,EC 2.7.10.1,DFNB97,AUTS9,RCCP2,C-Met,HGFR,Proto-Oncogene Proteins c-met
Number of Launched Drugs:9
Number of Drugs in Clinical Trials:61
Lastest Research Phase:Approved

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Synonym Name

MET,AUTS9,HGFR,RCCP2,c-Met

Background

The SARS-CoV-2 Spike S2-coupled Magnetic Beads is produced by coupling biotinylated SARS-CoV-2 spike S2 protein to streptavidin-conjugated magnetic beads. Because Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L, the biotinylated protein can bind to the SA beads irreversibly. The pre-coupled beads are ready to use for capturing anti-SARS-CoV-2 antibody or ACE2 protein from your sample with high specificity.

Clinical and Translational Updates

Related Molecule

HGF

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Crizotinib PF-1066; PF-2341066; PF-02341066; PF-002341066 Approved Pfizer Inc 赛可瑞, Xalkori United States Carcinoma, Non-Small-Cell Lung Pf Prism Cv 2011-08-26 Urethral Neoplasms; Neurilemmoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Granuloma, Plasma Cell; Endometrial Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lung Neoplasms; Lymphoma; Ureteral Neoplasms; Neuroblastoma; Solid tumours; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Uveal melanoma; Myofibroma; Multiple Myeloma; Neurofibromatosis 2; Kidney Diseases; Small Cell Lung Carcinoma; Neoplasms; Hematologic Neoplasms Details
Glumetinib HH-SCC244; SCC244; SCC-244 Approved Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd 海益坦 Mainland China Carcinoma, Non-Small-Cell Lung ShangHai HaiHe Biopharma Co Ltd 2023-03-07 Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Tepotinib hydrochloride hydrate MSC-2156119J; MSC-2156119; EMD-1214063 Approved Merck Serono Tepmetko, テプミトコ, TEPMETKO Japan Carcinoma, Non-Small-Cell Lung Merck KGaA, Darmstadt, Germany 2020-03-25 Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Capmatinib Hydrochloride NVP-INC280-NX; INCB-28060; C2A374O70X; INC-280; INCB-028060 Approved Incyte Corp, Novartis Pharma Ag Tabrecta United States Carcinoma, Non-Small-Cell Lung Novartis Pharmaceuticals Corp 2020-05-06 Glioblastoma; Carcinoma, Hepatocellular; Melanoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Gliosarcoma; Colorectal Neoplasms; Sarcoma; Liver Neoplasms; Adenocarcinoma of Lung; Triple Negative Breast Neoplasms; Neoplasms; Carcinoma, Renal Cell; Carcinoma; Kidney Neoplasms; Skin Melanoma; Solid tumours Details
Savolitinib HM-5016504; AZD-6094; HMP-504; HMPL-504 Approved Hutchison Medipharma Ltd 沃瑞沙, ORPATHYS Mainland China Carcinoma, Non-Small-Cell Lung Hutchison Medipharma Ltd 2021-06-22 Central Nervous System Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms, Neuroepithelial; Glioma; Carcinoma, Squamous Cell; Urologic Neoplasms; Diffuse Intrinsic Pontine Glioma; Colorectal Neoplasms; Peritoneal Neoplasms; Cholangiocarcinoma; Medulloblastoma; Kidney Diseases; Colonic Neoplasms; Neoplasms; Carcinoma; Stomach Neoplasms; Esophageal Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Solid tumours Details
Ensartinib Hydrochloride X-396 Approved Xcovery 贝美纳 Mainland China Carcinoma, Non-Small-Cell Lung Betta Pharmaceuticals Co Ltd 2020-11-17 Sarcoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Xanthogranuloma, Juvenile; Neuroectodermal Tumors, Primitive, Peripheral; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Brain metastases; Carcinoma, Squamous Cell; Glioma; Lymphoma, Non-Hodgkin; Lung Neoplasms; Histiocytic Sarcoma; Neuroblastoma; Solid tumours; Histiocytosis, Langerhans-Cell; Osteosarcoma; Sarcoma, Ewing; Central Nervous System Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Wilms Tumor; Rhabdoid Tumor; Hepatoblastoma; Medulloblastoma; Ependymoma; Rhabdomyosarcoma Details
Amivantamab CNTO-4424; JNJ-61186372; CNTO4424; JNJ-372; JNJ-6372 Approved Genmab A/S, Johnson & Johnson Innovative Medicine RYBREVANT United States Carcinoma, Non-Small-Cell Lung Janssen Biotech Inc 2021-05-21 Esophageal Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular Details
Cabozantinib S-malate XL-184; BMS-907351 Approved Exelixis Inc Cometriq, Cabometyx United States Carcinoma, Neuroendocrine; Thyroid Neoplasms Exelixis Inc 2012-11-29 Urethral Neoplasms; Leukemia, Myeloid, Acute; Thyroid Neoplasms; Gliosarcoma; Colorectal Neoplasms; Astrocytoma; Hepatic Insufficiency; Peritoneal Neoplasms; Bile Duct Neoplasms; Sarcoma, Clear Cell; Uterine Neoplasms; Adenocarcinoma, Clear Cell; Sarcoma, Ewing; Carcinoma, Adenosquamous; Breast Neoplasms; Neurofibroma, Plexiform; Osteosarcoma; Prostatic Neoplasms; Sarcoma; Medullary thyroid cancer (MTC); Carcinoma, Hepatocellular; Melanoma; Paraganglioma; Meningioma; Neoplasms, Germ Cell and Embryonal; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Brain Neoplasms; Carcinoma, Neuroendocrine; Sarcoma, Alveolar Soft Part; Lymphoma; Fallopian Tube Neoplasms; Brain metastases; Glioma; Endometrial Neoplasms; Carcinoma, Squamous Cell; Carcinoid Tumor; Glioblastoma; Skin Neoplasms; Neoplasms; Carcinoma, Papillary; Hepatoblastoma; Pheochromocytoma; Pain; Rejection of liver transplantation; Carcinoma, Renal Cell; Pancreatic neuroendocrine tumors Details
Vebreltinib PLB-1001; CBT-101; APL-101; CBI-3103 Approved Crown Bioscience Inc Mainland China Carcinoma, Non-Small-Cell Lung Beijing Purunao Biotechnology Co Ltd 2023-11-16 Solid tumours; Kidney Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Ganglioglioma; Pancreatic Neoplasms; Glioblastoma; Colonic Neoplasms; Brain Neoplasms; Lung Neoplasms; Thyroid Neoplasms; Glioma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
Crizotinib PF-1066; PF-2341066; PF-02341066; PF-002341066 Approved Pfizer Inc 赛可瑞, Xalkori United States Carcinoma, Non-Small-Cell Lung Pf Prism Cv 2011-08-26 Urethral Neoplasms; Neurilemmoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Granuloma, Plasma Cell; Endometrial Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lung Neoplasms; Lymphoma; Ureteral Neoplasms; Neuroblastoma; Solid tumours; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Uveal melanoma; Myofibroma; Multiple Myeloma; Neurofibromatosis 2; Kidney Diseases; Small Cell Lung Carcinoma; Neoplasms; Hematologic Neoplasms Details
Glumetinib HH-SCC244; SCC244; SCC-244 Approved Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd 海益坦 Mainland China Carcinoma, Non-Small-Cell Lung ShangHai HaiHe Biopharma Co Ltd 2023-03-07 Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Tepotinib hydrochloride hydrate MSC-2156119J; MSC-2156119; EMD-1214063 Approved Merck Serono Tepmetko, テプミトコ, TEPMETKO Japan Carcinoma, Non-Small-Cell Lung Merck KGaA, Darmstadt, Germany 2020-03-25 Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Capmatinib Hydrochloride NVP-INC280-NX; INCB-28060; C2A374O70X; INC-280; INCB-028060 Approved Incyte Corp, Novartis Pharma Ag Tabrecta United States Carcinoma, Non-Small-Cell Lung Novartis Pharmaceuticals Corp 2020-05-06 Glioblastoma; Carcinoma, Hepatocellular; Melanoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Gliosarcoma; Colorectal Neoplasms; Sarcoma; Liver Neoplasms; Adenocarcinoma of Lung; Triple Negative Breast Neoplasms; Neoplasms; Carcinoma, Renal Cell; Carcinoma; Kidney Neoplasms; Skin Melanoma; Solid tumours Details
Savolitinib HM-5016504; AZD-6094; HMP-504; HMPL-504 Approved Hutchison Medipharma Ltd 沃瑞沙, ORPATHYS Mainland China Carcinoma, Non-Small-Cell Lung Hutchison Medipharma Ltd 2021-06-22 Central Nervous System Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms, Neuroepithelial; Glioma; Carcinoma, Squamous Cell; Urologic Neoplasms; Diffuse Intrinsic Pontine Glioma; Colorectal Neoplasms; Peritoneal Neoplasms; Cholangiocarcinoma; Medulloblastoma; Kidney Diseases; Colonic Neoplasms; Neoplasms; Carcinoma; Stomach Neoplasms; Esophageal Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Solid tumours Details
Ensartinib Hydrochloride X-396 Approved Xcovery 贝美纳 Mainland China Carcinoma, Non-Small-Cell Lung Betta Pharmaceuticals Co Ltd 2020-11-17 Sarcoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Xanthogranuloma, Juvenile; Neuroectodermal Tumors, Primitive, Peripheral; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Brain metastases; Carcinoma, Squamous Cell; Glioma; Lymphoma, Non-Hodgkin; Lung Neoplasms; Histiocytic Sarcoma; Neuroblastoma; Solid tumours; Histiocytosis, Langerhans-Cell; Osteosarcoma; Sarcoma, Ewing; Central Nervous System Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Wilms Tumor; Rhabdoid Tumor; Hepatoblastoma; Medulloblastoma; Ependymoma; Rhabdomyosarcoma Details
Amivantamab CNTO-4424; JNJ-61186372; CNTO4424; JNJ-372; JNJ-6372 Approved Genmab A/S, Johnson & Johnson Innovative Medicine RYBREVANT United States Carcinoma, Non-Small-Cell Lung Janssen Biotech Inc 2021-05-21 Esophageal Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular Details
Cabozantinib S-malate XL-184; BMS-907351 Approved Exelixis Inc Cometriq, Cabometyx United States Carcinoma, Neuroendocrine; Thyroid Neoplasms Exelixis Inc 2012-11-29 Urethral Neoplasms; Leukemia, Myeloid, Acute; Thyroid Neoplasms; Gliosarcoma; Colorectal Neoplasms; Astrocytoma; Hepatic Insufficiency; Peritoneal Neoplasms; Bile Duct Neoplasms; Sarcoma, Clear Cell; Uterine Neoplasms; Adenocarcinoma, Clear Cell; Sarcoma, Ewing; Carcinoma, Adenosquamous; Breast Neoplasms; Neurofibroma, Plexiform; Osteosarcoma; Prostatic Neoplasms; Sarcoma; Medullary thyroid cancer (MTC); Carcinoma, Hepatocellular; Melanoma; Paraganglioma; Meningioma; Neoplasms, Germ Cell and Embryonal; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Brain Neoplasms; Carcinoma, Neuroendocrine; Sarcoma, Alveolar Soft Part; Lymphoma; Fallopian Tube Neoplasms; Brain metastases; Glioma; Endometrial Neoplasms; Carcinoma, Squamous Cell; Carcinoid Tumor; Glioblastoma; Skin Neoplasms; Neoplasms; Carcinoma, Papillary; Hepatoblastoma; Pheochromocytoma; Pain; Rejection of liver transplantation; Carcinoma, Renal Cell; Pancreatic neuroendocrine tumors Details
Vebreltinib PLB-1001; CBT-101; APL-101; CBI-3103 Approved Crown Bioscience Inc Mainland China Carcinoma, Non-Small-Cell Lung Beijing Purunao Biotechnology Co Ltd 2023-11-16 Solid tumours; Kidney Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Ganglioglioma; Pancreatic Neoplasms; Glioblastoma; Colonic Neoplasms; Brain Neoplasms; Lung Neoplasms; Thyroid Neoplasms; Glioma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
HS-10241 HS-10241 Phase 3 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Solid tumours; Carcinoma; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Zanzalintinib XL-092 Phase 3 Clinical Exelixis Inc Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Recombinant plasmid-hepatocyte growth factor Pudk-HGF Phase 3 Clinical Wuhan Optical Valley Humanwell Biological Pharmaceutical Co Ltd, Academy Of Military Medical Sciences Ischemia; Peripheral Arterial Disease Details
Refanalin ANG-3777; BB-3; SNV-003 Phase 3 Clinical Vifor Pharma Ag, Elicio Therapeutics Myocardial Infarction; Pneumonia; Coronavirus Disease 2019 (COVID-19); Acute Kidney Injury; Delayed Graft Function Details
Fosgonimeton ATH-1017; NDX-1017 Phase 3 Clinical M3 Biotechnology Alzheimer Disease; Lewy Body Disease Details
Sitravatinib MG-91516; MGCD-516; IND-155305; MG-516 Phase 3 Clinical Mirati Therapeutics Inc Breast Neoplasms; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Metastatic breast cancer; Mouth Neoplasms; Endometrial Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Lung Neoplasms; Ureteral Neoplasms; Hepatic Insufficiency; Solid tumours; Liposarcoma; Uveal melanoma; Lung Diseases; Carcinoma, Transitional Cell; Neoplasms; Triple Negative Breast Neoplasms; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Biliary Tract Neoplasms; Kidney Neoplasms Details
SC-0011 SC-0011 Phase 3 Clinical Shijiazhuang Zhikang Hongren New Drug Development Co Ltd Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Telisotuzumab vedotin ABT-399; ABBV-399 Phase 3 Clinical Abbvie Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
AL-2846 AL-2846 Phase 3 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Advenchen Laboratories Nanjing Ltd Neoplasms; Carcinoma, Non-Small-Cell Lung; Neurofibromatosis 1; Neurilemmoma; Lung Neoplasms; Thyroid Neoplasms; Colorectal Neoplasms; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Solid tumours; Ganglioglioma; Neurofibroma; Neurofibromatoses; Pancreatic Neoplasms; Stomach Neoplasms; Bone metastases; Ovarian Neoplasms; Liver Neoplasms Details
Ningetinib Tosylate CT-053-PTSA; CT-053 Phase 2 Clinical Hec Pharm Co Ltd Intestinal Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Pamvatamig MCLA-129 Phase 2 Clinical Merus Nv Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
Merestinib 5OGS5K699E; LY-2801653 Phase 2 Clinical Eli Lilly And Company Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Sym-015 Sym-015 Phase 2 Clinical Symphogen A/S Neoplasms; Carcinoma, Non-Small-Cell Lung Details
ABN-401 ABN-401; KDDF-201603-08 Phase 2 Clinical Abion Inc Solid tumours; Neoplasms Details
REGN-5093-M114 METxMET-M114; REGN5093-M114 Phase 2 Clinical Carcinoma, Non-Small-Cell Lung Details
Glesatinib MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265 Phase 2 Clinical Mirati Therapeutics Inc Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bafisontamab FIT-013a; EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Biliary Tract Neoplasms; Liver Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
GB-263 GB-263; GB-263T Phase 2 Clinical Genor Biopharma Co Ltd Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Elzovantinib TPX-0022 Phase 2 Clinical Turning Point Therapeutics Inc Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Do-1 Do-1 Phase 2 Clinical DeuterOncology NV Lung Neoplasms Details
EMI-137 EMI-137; GE-137 Phase 2 Clinical Ge Healthcare Esophageal Neoplasms; Colonic Neoplasms; Extranodal Extension; Barrett Esophagus Details
Davutamig REGN-5093 Phase 2 Clinical Carcinoma, Non-Small-Cell Lung Details
CKD-702 Phase 2 Clinical Chong Kun Dang Pharmaceutical Corp Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Recombinant adenovirus-hepatocyte growth factor(Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences) Phase 2 Clinical Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences, Beijing Haitai United Pharmaceutical Technology Development Co Ltd Myocardial Ischemia Details
RC-108 RC-108; RC108 Phase 2 Clinical RemeGen Co Ltd Solid tumours; Digestive System Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Emibetuzumab LA-480; LY-2875358 Phase 2 Clinical Eli Lilly And Company Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Neoplasms; Lymphoma; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
SHR-A1403 SHR-A1403 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours Details
CM-118 CM-118 Phase 1 Clinical Xcovery Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Kanitinib CX-1003 Phase 1 Clinical Beijing Konruns Pharmaceutical Co Ltd, Guangzhou Yingsheng Bio Technology Co Ltd Solid tumours Details
BPI-9016 BPI-9016; BPI-9016M Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
HLX-55 HLX-55; KTN-0216 Phase 1 Clinical Kolltan Pharmaceuticals Inc Solid tumours Details
Pamufetinib TAS-115 Phase 1 Clinical Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd Neoplasms Details
Boxitinib Hydrochloride Phase 1 Clinical Hec Pharm Co Ltd Stomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms Details
BYON-3521 BYON-3521 Phase 1 Clinical Byondis Bv Solid tumours; Neoplasms Details
ATH-1020 ATH-1020 Phase 1 Clinical Athira Pharma Inc Details
QBH-196 QBH-196 Phase 1 Clinical Shenyang Pharmaceutical University Solid tumours; Stomach Neoplasms Details
[11C]savolitinib [11C]savolitinib Phase 1 Clinical Astrazeneca Plc Details
[14C]HS-10241 [14C]HS-10241 Phase 1 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Carcinoma, Non-Small-Cell Lung Details
FPI-2107 [111In]-FPI-2107 Phase 1 Clinical Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
FPI-2053 FPI-2053 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
ANS-014004 ANS014004; ANS-014004; ANS-01; ANS01 Phase 1 Clinical Beijing Avistone Pharmaceuticals Biotechnology Co Ltd Solid tumours; Neoplasms Details
FPI-2068 [225Ac]-FPI-2068; FPI-2068 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
SPH-3348 SPH-3348; SPH3348; I-020 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours; Neoplasms Details
HS-20117 HS-20117; PM1080; PM-1080 Phase 1 Clinical Biotheus Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
MYTX-011 MYTX-011 Phase 1 Clinical Mythic Therapeutics Inc Carcinoma, Non-Small-Cell Lung Details
AZD9592 AZD-9592; AZD9592 Phase 1 Clinical Astrazeneca Plc Solid tumours; Head and Neck Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
TAVO-412 TAVO-412 Phase 1 Clinical Tavotek Biotherapeutics (Hong Kong) Ltd, Tuochuang Biotechnology (Jiangsu) Co Ltd Solid tumours; Neoplasms Details
ABBV-400 ABBV-400 Phase 1 Clinical Abbvie Inc Biliary Tract Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Squamous Cell Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
NP-107 NP107; NP-107 Phase 1 Clinical Shanghai Nawei Biotechnology Co Ltd Solid tumours Details
ASKC-202 ASKC202 Phase 1 Clinical Jiangsu Aosaikang Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
LMV-12(HE003) LMV-12(HE003) Phase 1 Clinical Nanchang Hongyi Technology Co Ltd Solid tumours Details
GST-HG161 GST-HG161 Phase 1 Clinical Wuxi Apptec Co Ltd, Fujian Cosunter Pharmaceutical Co Ltd Solid tumours; Neoplasms; Carcinoma, Hepatocellular Details
Metatinib Trometamol BMS-817378; SIM-817378 Phase 1 Clinical Bristol-Myers Squibb Company Solid tumours; Liver Neoplasms; Stomach Neoplasms; Colorectal Neoplasms Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology) NP-01 Phase 1 Clinical Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd Solid tumours; Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms Details
SAIT-301 SAIT-301 Phase 1 Clinical Samsung Medical Center Neoplasms Details
NPS-1034 HOPE-777; KDDF-201111-02 Neopharma Ltd Details
CGT-1403 CGT-1403 Cgenetech(Suzhou China) Co Ltd Neoplasms Details
HS-10241 HS-10241 Phase 3 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Solid tumours; Carcinoma; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Zanzalintinib XL-092 Phase 3 Clinical Exelixis Inc Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Recombinant plasmid-hepatocyte growth factor Pudk-HGF Phase 3 Clinical Wuhan Optical Valley Humanwell Biological Pharmaceutical Co Ltd, Academy Of Military Medical Sciences Ischemia; Peripheral Arterial Disease Details
Refanalin ANG-3777; BB-3; SNV-003 Phase 3 Clinical Vifor Pharma Ag, Elicio Therapeutics Myocardial Infarction; Pneumonia; Coronavirus Disease 2019 (COVID-19); Acute Kidney Injury; Delayed Graft Function Details
Fosgonimeton ATH-1017; NDX-1017 Phase 3 Clinical M3 Biotechnology Alzheimer Disease; Lewy Body Disease Details
Sitravatinib MG-91516; MGCD-516; IND-155305; MG-516 Phase 3 Clinical Mirati Therapeutics Inc Breast Neoplasms; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Metastatic breast cancer; Mouth Neoplasms; Endometrial Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Lung Neoplasms; Ureteral Neoplasms; Hepatic Insufficiency; Solid tumours; Liposarcoma; Uveal melanoma; Lung Diseases; Carcinoma, Transitional Cell; Neoplasms; Triple Negative Breast Neoplasms; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Biliary Tract Neoplasms; Kidney Neoplasms Details
SC-0011 SC-0011 Phase 3 Clinical Shijiazhuang Zhikang Hongren New Drug Development Co Ltd Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Telisotuzumab vedotin ABT-399; ABBV-399 Phase 3 Clinical Abbvie Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
AL-2846 AL-2846 Phase 3 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Advenchen Laboratories Nanjing Ltd Neoplasms; Carcinoma, Non-Small-Cell Lung; Neurofibromatosis 1; Neurilemmoma; Lung Neoplasms; Thyroid Neoplasms; Colorectal Neoplasms; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Solid tumours; Ganglioglioma; Neurofibroma; Neurofibromatoses; Pancreatic Neoplasms; Stomach Neoplasms; Bone metastases; Ovarian Neoplasms; Liver Neoplasms Details
Ningetinib Tosylate CT-053-PTSA; CT-053 Phase 2 Clinical Hec Pharm Co Ltd Intestinal Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Pamvatamig MCLA-129 Phase 2 Clinical Merus Nv Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
Merestinib 5OGS5K699E; LY-2801653 Phase 2 Clinical Eli Lilly And Company Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Sym-015 Sym-015 Phase 2 Clinical Symphogen A/S Neoplasms; Carcinoma, Non-Small-Cell Lung Details
ABN-401 ABN-401; KDDF-201603-08 Phase 2 Clinical Abion Inc Solid tumours; Neoplasms Details
REGN-5093-M114 METxMET-M114; REGN5093-M114 Phase 2 Clinical Carcinoma, Non-Small-Cell Lung Details
Glesatinib MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265 Phase 2 Clinical Mirati Therapeutics Inc Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bafisontamab FIT-013a; EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Biliary Tract Neoplasms; Liver Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
GB-263 GB-263; GB-263T Phase 2 Clinical Genor Biopharma Co Ltd Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Elzovantinib TPX-0022 Phase 2 Clinical Turning Point Therapeutics Inc Solid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Do-1 Do-1 Phase 2 Clinical DeuterOncology NV Lung Neoplasms Details
EMI-137 EMI-137; GE-137 Phase 2 Clinical Ge Healthcare Esophageal Neoplasms; Colonic Neoplasms; Extranodal Extension; Barrett Esophagus Details
Davutamig REGN-5093 Phase 2 Clinical Carcinoma, Non-Small-Cell Lung Details
CKD-702 Phase 2 Clinical Chong Kun Dang Pharmaceutical Corp Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Recombinant adenovirus-hepatocyte growth factor(Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences) Phase 2 Clinical Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences, Beijing Haitai United Pharmaceutical Technology Development Co Ltd Myocardial Ischemia Details
RC-108 RC-108; RC108 Phase 2 Clinical RemeGen Co Ltd Solid tumours; Digestive System Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Emibetuzumab LA-480; LY-2875358 Phase 2 Clinical Eli Lilly And Company Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Neoplasms; Lymphoma; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
SHR-A1403 SHR-A1403 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours Details
CM-118 CM-118 Phase 1 Clinical Xcovery Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Kanitinib CX-1003 Phase 1 Clinical Beijing Konruns Pharmaceutical Co Ltd, Guangzhou Yingsheng Bio Technology Co Ltd Solid tumours Details
BPI-9016 BPI-9016; BPI-9016M Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
HLX-55 HLX-55; KTN-0216 Phase 1 Clinical Kolltan Pharmaceuticals Inc Solid tumours Details
Pamufetinib TAS-115 Phase 1 Clinical Taiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co Ltd Neoplasms Details
Boxitinib Hydrochloride Phase 1 Clinical Hec Pharm Co Ltd Stomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms Details
BYON-3521 BYON-3521 Phase 1 Clinical Byondis Bv Solid tumours; Neoplasms Details
ATH-1020 ATH-1020 Phase 1 Clinical Athira Pharma Inc Details
QBH-196 QBH-196 Phase 1 Clinical Shenyang Pharmaceutical University Solid tumours; Stomach Neoplasms Details
[11C]savolitinib [11C]savolitinib Phase 1 Clinical Astrazeneca Plc Details
[14C]HS-10241 [14C]HS-10241 Phase 1 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Carcinoma, Non-Small-Cell Lung Details
FPI-2107 [111In]-FPI-2107 Phase 1 Clinical Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
FPI-2053 FPI-2053 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
ANS-014004 ANS014004; ANS-014004; ANS-01; ANS01 Phase 1 Clinical Beijing Avistone Pharmaceuticals Biotechnology Co Ltd Solid tumours; Neoplasms Details
FPI-2068 [225Ac]-FPI-2068; FPI-2068 Phase 1 Clinical Astrazeneca Plc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
SPH-3348 SPH-3348; SPH3348; I-020 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours; Neoplasms Details
HS-20117 HS-20117; PM1080; PM-1080 Phase 1 Clinical Biotheus Inc Solid tumours; Carcinoma, Non-Small-Cell Lung Details
MYTX-011 MYTX-011 Phase 1 Clinical Mythic Therapeutics Inc Carcinoma, Non-Small-Cell Lung Details
AZD9592 AZD-9592; AZD9592 Phase 1 Clinical Astrazeneca Plc Solid tumours; Head and Neck Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
TAVO-412 TAVO-412 Phase 1 Clinical Tavotek Biotherapeutics (Hong Kong) Ltd, Tuochuang Biotechnology (Jiangsu) Co Ltd Solid tumours; Neoplasms Details
ABBV-400 ABBV-400 Phase 1 Clinical Abbvie Inc Biliary Tract Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Squamous Cell Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
NP-107 NP107; NP-107 Phase 1 Clinical Shanghai Nawei Biotechnology Co Ltd Solid tumours Details
ASKC-202 ASKC202 Phase 1 Clinical Jiangsu Aosaikang Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
LMV-12(HE003) LMV-12(HE003) Phase 1 Clinical Nanchang Hongyi Technology Co Ltd Solid tumours Details
GST-HG161 GST-HG161 Phase 1 Clinical Wuxi Apptec Co Ltd, Fujian Cosunter Pharmaceutical Co Ltd Solid tumours; Neoplasms; Carcinoma, Hepatocellular Details
Metatinib Trometamol BMS-817378; SIM-817378 Phase 1 Clinical Bristol-Myers Squibb Company Solid tumours; Liver Neoplasms; Stomach Neoplasms; Colorectal Neoplasms Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology) NP-01 Phase 1 Clinical Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd Solid tumours; Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms Details
SAIT-301 SAIT-301 Phase 1 Clinical Samsung Medical Center Neoplasms Details
NPS-1034 HOPE-777; KDDF-201111-02 Neopharma Ltd Details
CGT-1403 CGT-1403 Cgenetech(Suzhou China) Co Ltd Neoplasms Details

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