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NGFR

Brief Information

Name:Low affinity neurotrophin receptor p75NTR
Target Synonym:Gp80-LNGFR,P75NTR,CD271 Antigen,Low-Affinity Nerve Growth Factor Receptor,Tumor Necrosis Factor Receptor Superfamily Member 16,Low Affinity Nerve Growth Factor Receptor,Low Affinity Neurotrophin Receptor P75NTR,Nerve Growth Factor Receptor (TNFR Superfamily, Member 16),TNFR Superfamily, Member 16,Nerve Growth Factor Receptor,P75 ICD,P75(NTR),TNFRSF16,CD271
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
CHEK-ATP157 Human HEK293/Human NGFR Stable Cell Line
NGR-H5254 Human Human NGFR / TNFRSF16 Protein, Fc Tag (MALS verified)
NGR-H5254-structure
NGR-H5254-sds
ACRO Quality

Part of Bioactivity data

CHEK-ATP157-Cell-based assay
 NGFR FACS

Expression analysis of human NGFR on HEK293/Human NGFR Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human NGFR Stable Cell Line or negative control cell using PE-labeled anti-human NGFR antibody after fixation with 4% paraformaldehyde.

NGR-H5254-BLI
 NGFR BLI

Loaded Human NGFR Protein, Fc Tag (Cat. No. NGR-H5254) on Protein A Biosensor, can bind Human NT-4, Tag Free (Cat. No. NT4-H5114) with an affinity constant of 1.64 nM as determined in BLI assay (ForteBio Octet Red96e) (QC tested).

NGR-H5254-MALS-HPLC
NGFR MALS images

The purity of Human NGFR Protein, Fc Tag (Cat. No. NGR-H5254) is more than 95% and the molecular weight of this protein is around 115-135 kDa verified by SEC-MALS.

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
LM11A-31 LM11A-31; LM11A-31-BHS Phase 2 Clinical Pharmatrophix Inc Alzheimer Disease Details
Recombinant Human Nerve Growth Factor (Kerun Biopharmaceutical) Phase 1 Clinical Chongqing Kerun Biologic Pharmaceutical Development Co Ltd Keratitis; Xerophthalmia Details

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