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Claudin-1

Brief Information

Name:Claudin 1
Target Synonym:Claudin-1,SEMP1,ILVASC,CLD1,Senescence-Associated Epithelial Membrane Protein 1,CLDN1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase 2 Clinical

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
CHEK-ATP124 Human HEK293/Human Claudin-1 Stable Cell Line
CL1-H52P6 Human Human Claudin-1 Full Length Protein (VLP)
CL1-H55D8 Human Human Claudin-1 Protein, Flag,His Tag (Detergent)
CL1-H55D8-structure
CL1-H55D8-sds
ACRO Quality

Part of Bioactivity data

CHEK-ATP124-Cell-based assay
 Claudin-1 FACS

Expression analysis of human Claudin-1 on HEK293/Human Claudin-1 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Claudin-1 Stable Cell Line or negative control cell using
anti-human Claudin-1 antibody followed by staining with FITC anti-mouse IgG Fc Antibody.

CL1-H55D8-ELISA
 Claudin-1 ELISA

Immobilized Human Claudin-1 Protein, Flag,His Tag (Cat. No. CL1-H55D8) at 5 μg/mL (100 μL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human Claudin-1 antibody, Human IgG1 with a linear range of 0.001-0.625 μg/mL (QC tested).

CL1-H52P6-ELISA
 Claudin-1 ELISA

Immobilized Human Claudin-1 Full Length Protein (VLP) (Cat. No. CL1-H52P6) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Claudin-1 antibody, Human IgG1 with a linear range of 0.3-20 ng/mL (QC tested).

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
ALE-C04 ALE-C04; ALE.C04 Phase 2 Clinical Inserm Head and Neck Neoplasms; Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Cholangiocarcinoma Details
ALE-P02 ALE-P02; ALE.P02 Phase 2 Clinical Alentis Therapeutics AG Solid tumours; Squamous Cell Carcinoma of Head and Neck; Esophageal Squamous Cell Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Lixudebart ALE-F02; ALE-F-02 Phase 2 Clinical Alentis Therapeutics AG Liver Cirrhosis; Renal fibrosis; Glomerulonephritis Details

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