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FGF-9

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
FG9-H52H3 Human Human FGF-9 Protein, His Tag
FG9-H52H3-structure
FG9-H52H3-sds
FG9-H4267 Human Human FGF-9 Protein, Fc Tag
FG9-H4267-structure
FG9-H4267-sds
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Part of Bioactivity data

FG9-H4267-SPR
FGF-9 SPR

Human FGF R3 (IIIc), Fc Tag (Cat. No. FGC-H5256) immobilized on CM5 Chip can bind Human FGF-9, Fc Tag (Cat. No. FG9-H4267) with an affinity constant of 10.5 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
FG9-H52H3-BLI
FGF-9 BLI

Loaded Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) on Protein A Biosensor, can bind Human FGF-9, His Tag (Cat. No. FG9-H52H3) with an affinity constant of 119 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

FGF9,GAF,HBFG-9,MGC119914,MGC119915,SYNS3

Background

Fibroblast growth factor 9 is also known as FGF9, GAF, HBFG-9, SYNS3, and  is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF9 is also a mitogen for oligodendrocyte type 2 astrocyte progenitor cells, smooth muscle cells, pheochromocytoma PC12 cells, and BALB/3T3 fibroblasts. However, unlike FGF acidic and basic, FGF9 has no effect on human umbilical vein endothelial cells, and it has been demonstrated that FGF9 binds preferentially to the IIIc form of FGFR3. Although no typical signal sequence was found in FGF9, it is secreted efficiently after synthesis not in a conventional manner. In nervous system, FGF9 is produced mainly by neurons and may plays an important role in CNS development. FGF9 has been shown to interact with Fibroblast growth factor receptor 3.

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