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IL-27 Ra

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
ILA-H52Hb Human Human IL-27 Ra / TCCR Protein, His Tag (MALS verified)
ILA-H52Hb-structure
ILA-H52Hb-sds
ILA-H5254 Human Human IL-27 Ra / TCCR Protein, Fc Tag
ILA-H5254-structure
ILA-H5254-sds
ACRO Quality

Part of Bioactivity data

ILA-H5254-SPR
 IL-27 Ra SPR

Human IL-27 Ra Protein, Fc Tag (Cat. No. ILA-H5254) immobilized on CM5 Chip can bind Human IL-27 Protein, Fc Tag, premium grade (Cat. No. IL7-H5254) with an affinity constant of 3.67 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

ILA-H52Hb-MALS-HPLC
IL-27 Ra MALS images

The purity of Human IL-27 Ra Protein, His Tag (Cat. No. ILA-H52Hb) is more than 85% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

Synonym Name

IL27RA,CRL1,TCCR,WSX1

Background

Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.

Clinical and Translational Updates

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