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Cat . Non | Espèces | Description du produit | Structure | Pureté | Caractéristique |
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PD2-M82E3 | Mouse | Biotinylated Mouse PD-L2 / B7-DC Protein, His,Avitag™ (MALS verified) |
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PD2-H82F6 | Human | Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag™ (MALS verified) |
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PD2-M5254 | Mouse | Mouse PD-L2 / B7-DC Protein, Fc Tag |
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PD2-H82E8 | Human | Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag (recommended for biopanning) |
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PD2-M52E3 | Mouse | Mouse PD-L2 / B7-DC Protein, His Tag (MALS verified) |
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PD2-H52A5 | Human | Human PD-L2 / B7-DC Protein, Mouse IgG1 Fc Tag |
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PD2-H5251 | Human | Human PD-L2 / B7-DC Protein, Fc Tag (HPLC verified) |
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PD2-H5220 | Human | Human PD-L2 / B7-DC Protein, His Tag (SPR verified) |
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Flow Cytometry assay shows that Human PD-L2, Mouse IgG1 Fc Tag (Cat. No. PD2-H52A5) can bind to 293 cell overexpressing human PD-1. The concentration of PD-L2 used is 0.1 μg/mL (Routinely tested).
FACS analysis shows that the binding of Human PD-L2, Mouse IgG1 Fc Tag (Cat. No. PD2-H52A5) to 293 overexpressing PD-1 was inhibited by increasing concentration of neutralizing Anti-PD-1 antibody. The concentration of PD-L2 used is 0.1 μg/mL. The IC50 is 1.3 μg/mL (Routinely tested).
Captured Human PD-L2 Protein, His Tag (Cat. No. PD2-H5220) on CM5 Chip via anti-His antibody can bind Human PD-1, Fc Tag (Cat. No. PD1-H5257) with an affinity constant of 24.9 nM as determined in SPR assay (Biacore T200) (QC tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
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IMGS-001 | IMGS-001 | Phase 1 Clinical | The University Of Texas MD Anderson Cancer Center | Solid tumours; Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms | Details |
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