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BMP-4

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
GMP-BM4H18 Human GMP Human BMP-4 / BMP2B (improved sequence) Protein
BM4-H5317 Human Human BMP-4 / BMP2B Protein, premium grade
BM4-H5317-structure
BM4-H5317-sds
BM4-H5118 Human Human BMP-4 / BMP2B (improved sequence) Protein, premium grade
BM4-H5118-sds
ACRO Quality

Part of Bioactivity data

BM4-H5118-Cell-based assay
 BMP-4 CELL

Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) stimulates proliferation of Human BMP (Luc) HEK293 Reporter Cell (Cat. No. CHEK-ATF188). The specific activity of Human BMP-4 (improved sequence) Protein, premium grade is > 1.9 x 10^3 U/mg (QC tested).

Synonym Name

BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME

Background

Bone Morphogenetic Protein 4 (BMP4) is a member of growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. BMP-4 Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. BMP-4 can acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Clinical and Translational Updates

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