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EDIL3

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
ED3-H5259 Human Human EDIL3 Protein, Fc Tag
ED3-H5259-structure
ED3-H5259-sds
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Part of Bioactivity data

ED3-H5259-SPR
EDIL3 SPR

Human EDIL3, Fc Tag (Cat. No. ED3-H5259) immobilized on CM5 Chip can bind Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT3-H52E3) with an affinity constant of 38.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
ED3-H5259-ELISA
EDIL3 ELISA

Immobilized Human EDIL3, Fc Tag (Cat. No. ED3-H5259) at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGAV&ITGB3 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT3-H82W9) with a linear range of 0.02-0.625 μg/mL (QC tested).

Protocol

Synonym Name

DEL1,EDIL3

Background

EDIL3, also known as Del1, is a novel extracellular matrix protein encoding three Notch-like epidermal growth factor repeats, an RGD motif, and two discoidin domains. EDIL3 is expressed in an endothelial cell-restricted pattern during early development. EDIL3 might involves autocrine angiogenic pathway for the embryonic endothelium, and this function is mediated in part by productive ligation of integrin alpha V beta 3. Overall, EDIL3 plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. Moreover, It also influences endothelial cell behavior.

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