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DR3

Brief Information

Name:Tumor necrosis factor receptor superfamily member 25
Target Synonym:Apo-3,Apoptosis-inducing receptor AIR,Apoptosis-mediating receptor DR3,Apoptosis-mediating receptor TRAMP,Death receptor 3,Lymphocyte-associated receptor of death,Protein WSL,DDR3,Death Receptor Beta,TNFRSF12,TRAMP,DR3,WSL-1,PH Domain-Containing Family G Member 5,PLEKHG5,WSL-LR,WSL1,APO3,WSL,TR3,TNF Receptor Superfamily Member 25,Death Domain Receptor 3 Soluble Form,GEF720,Guanine Nucleotide Exchange Factor 720,Apoptosis Inducing Receptor,Tumor Necrosis Factor Receptor Superfamily, Member 25,Ple
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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Part of Bioactivity data

DR3-C52H3-SPR
 DR3 SPR

Cynomolgus DR3 Protein, His Tag (Cat. No. DR3-C52H3) immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TL1A / TNFSF15, His Tag (Cat. No. TLA-C5241) with an affinity constant of 94.7 nM as determined in a SPR assay (Biacore 8K) (QC tested).

DR3-H82E3-SPR
 DR3 SPR

Biotinylated Human DR3 Protein, His,Avitag (Cat. No. DR3-H82E3) captured on Biotin CAP-Series S Sensor Chip can bind Human TL1A, His Tag (Cat. No. TLA-H5243) with an affinity constant of 1.75 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

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